Polyimide sieve electrodes

Navarro, X. Calvet, S. Rodriguez, F. J. Stieghtz, T. Blau, C. But , M. Valderrama, E. Meyer, J.-U. Stimulation and Recording from Regenerated Peripheral Nerves through Polyimide Sieve Electrodes. J. Peripheral Nervous Sys. (3) 2 (1998), pp. 91-101... 

Fig. 5 (A) Silicon sieve electrode and (B) close-up view of the iridium-lined site [40]. Reproduced with permission. (C) Regenerative sieve electrode severed nerve fibers grow through the holes of the sieve structure [20]. (D) Polyimide sieve electrode assembled with guidance channel [42]...

Klinge PM, Vafa MA, Brinker T (2001) Immunohistochemiceil characterization of axonal sprouting tmd reactive tissue cheinges after long-term implantation of a polyimide sieve electrode to the transected adult rat sciatic nerve. Biomaterials 22 2333-2343. 

Micromachined flexible, neural electrodes have been designed and manufactured for contacting the tightly packed neural elements in the nerve trunk [30,31], Polyimide was chosen as the substrate and insulation material for a design of multichannel sieve electrodes with integrated interconnects... 

Fig. 9.28. Flexible, polyimide based sieve electrodes interfacing regenerating axons in peripheral nerves...

Thin-film polyimide-based implants use the polymer as both the structural and insulation material. They have been micromachined with multilayer metallization [54] for use as acute and chronic extracellular recording electrodes, and sieve and cuff regeneration electrodes. Thin-film metal layers (approximately 200-300 nm thickness) are sandwiched between the polymer layers. Reactive ion etching in oxygen opens contacts to the electrodes. This dry etch also defines the probe shape (Fig. 7). 

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