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Polyhydroxyalkanoate tissue engineering

Abstract Polyhydroxyalkanoate (PHA) is a plastic-like material synthesized by many bacteria. PHA serves as an energy and carbon storage componnd for the bacteria. PHA can be extracted and purified from the bacterial cells and the resulting product resembles some commodity plastics such as polypropylene. Because PHA is a microbial product, there are natural enzymes that can degrade and decompose PHA. Therefore, PHA is an attractive material that can be developed as a bio-based and biodegradable plastic. In addition, PHA is also known to be biocompatible and can be used in medical devices and also as bioresorbable tissue engineering scaffolds. In this chapter, a brief introduction about PHA and the fermentation feedstock for its production are given. [Pg.1]

Chen G-Q, Wu Q (2005) The apphcation of polyhydroxyalkanoates as tissue engineering materials. Biomaterials 26 6565-6578... [Pg.106]

Sudesh K (2004) Microbial polyhydroxyalkanoates (PHAs) an emerging biomaterial for tissue engineering and therapeutic applications. Med J Malays 59 Suppl B 55-56 Sudesh K, Abe H (2010) Practical guide to microbial polyhydroxyalkanoates. Smithers Rapra Technology, UK... [Pg.125]

Misra SK, ValappU S, Roy I, Boccaccini AR (2006) Polyhydroxyalkanoate (PHA)/inorganic phase composites for tissue engineering applications. Biomacromolecules 7 2249-2258 Mitschke U, Bauerle P (2000) The electroluminescence of organic materials. J Mater Chem 10 1471-1507... [Pg.15]

Chen GQ and Wu Q (2005) Polyhydroxyalkanoates as tissue engineering materieils. Biomaterieds... [Pg.35]

CeccomUi G, PizzoU M, Scandola M (1993) Effect of a low-molecular-weight plasticizer on the thermal and viscoelastic properties of miscible blends of bacterial poly(3-hydroxybutyrate) with cellulose acetate butyrate. Macromolecules 26 6722-6726 Chanprateep S, Kikuya K, Shimizu H, Shioya S (2(X)2) Model predictive controller for biodegradable polyhydroxyalkanoate production in fed-batch culture. J Bacterid 95 157-169 Chen GQ, Wu Q (2005) The application of polyhydroxyalkanoates as tissue engineering materials. Biomaterials 26 6565-6578... [Pg.171]

Cameron NS, Corbierre MK, Eisenberg A (1999) Asymmetric amphiphilic block copolymers in solution a morphological wonderland. Can J Chem 77 1311-1326 Cheng GQ, Wu Q (2005) The application of polyhydroxyalkanoates as tissue engineering materials. Biomaterials 26 6565-6578... [Pg.314]

Polyhydroxyalkanoates (PHAs) are polyesters synthesized by many bacteria. These polymers are accumulated intracellularly imder nutrient stress and act as a carbon and energy reserve. PHAs are non-toxic, biodegratkble and biocompatible. They are produced from renewable sources. They have high degree of polymerization, are highly crystalline, isotactic and insoluble in water. Because of these properties, PHAs have a real potential in medical and pharmaceutical applications, such as drug delivery systems and tissue engineering. [Pg.78]

Sodian R, Sperling JS, Martin DP, Egozy A, Stock U, Mayer JE, Vacanti JP. Fabrication of a trileaflet heart valve scaffold from a polyhydroxyalkanoate biopolyester for use in tissue engineering. Tissue Eng 2000 6 183-188. [Pg.167]

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See also in sourсe #XX -- [ Pg.372 ]



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Polyhydroxyalkanoate

Polyhydroxyalkanoates tissue engineering

Polyhydroxyalkanoates tissue engineering

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