Polyethylene glycol features

It has long been recognized that polymeric supports for oligosaccharide synthesis do not need to be insoluble.33 Wang et al. applied the sulfoxide glycosylation method to the synthesis of disaccharide 79 (Scheme 3.14). The key feature of this work was the base-labile linker. Sulfoxide 74 was used to glycosylate polyethylene glycol... 

All peptide-catalyzed enone epoxidations described so far were performed using insoluble, statistically polymerized materials (neat or on solid supports). One can, on the other hand, envisage (i) generation of solubilized poly-amino acids by attachment to polyethylene glycols (PEG) and (ii) selective construction of amino acid oligomers by standard peptide synthesis-linked to a solid support, to a soluble PEG, or neat as a well-defined oligopeptide. Both approaches have been used. The former affords synthetically useful and soluble catalysts with the interesting feature that the materials can be kept in membrane reactors for continuously oper-... 

Blawas AS, Oliver TF, Pirrung MC et al (1998) Step-and-repeat photopatteming of protein features using caged/biotin-BSA characterization and resolution. Langmuir 14 4243 250 Conrad DW, Golightley SK, Bart JC (1998) Photoactivatable o-nitrobenzyl polyethylene glycol-silane for the production of patterned biomolecular arrays. US Patent 5,773,308... 

This review is divided into four main sections, covering the Heck, Stille, and Suzuki reactions, with miscellaneous reactions being included at the end. Processes featuring alkynes in copper co-catalyzed Sonogashira-type couplings have been included in the section on Heck reactions. This review does not cover carbon-carbon bond formation processes using immobilized catalysts. Similarly, fluorous-phase syntheses " and those on polyethylene glycol " are excluded. 

Polyethylene glycol) is a polymer produced in various lengths, containing from several to many hundred monomers. It exhibits as its most conspicuous feature a regular alteration... 

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