Poly monodendron

GPC proved to be a method extraordinarily well suited to the analysis and purification of 9-phenylcarbazole monodendrons, naturally branched polymers.12 Monodendrons up to generation four, molecular weight 16.6 kDa, were separated by GPC. Branching, introduced into bacterially produced poly(hydroxy butyrate) by co-polymerization with hydroxyvaleric acid, was analyzed by GPC in chloroform with on-line viscometry.13... 

Figure 11.38 (Left) Fourth generation monodendron with a hexaethylene glycol tail. (Right) Proposed conformations of poly(benzyl ethyl ether) monodendrons oriented at the air-water interface.

Kampf JP, Frank CW, Malmstroem EE, Hawker CJ. Stability and molecular conformation of poly(benzyl ether) monodendrons with oligo(ethylene glycol) tails at the air-water interface. Langmuir 1999 15 227-233. 

Hydrodynamic radii of poly(benzyl ether) dendrimers are shown in Fig. 5. Data for monodendrons with a hydroxyl focal group and tridendrons fall on the same curve. The value of the exponent v in Eq. (4) is 0.46 of low MW. At high MW it is 0.26 [48]. Data on low MW linear polystyrene in benzene [74] have been included in Fig. 5 for comparison. They highlight the little difference in the actual values of the hydrodynamic radii of linear polystyrene and low MW poly(benzyl ether) dendrimers. Deviations are observed only when MW>5xl03. Furthermore, the MW dependence of the radii of polystyrene and poly(benzyl ether) dendrimers are the same at low MW. This indicates that it remains impossible to draw major conclusions about the conformation of the low MW dendrimers from their global properties. The low values of the hydrodynamic radii of the high MW dendrimers, on the other hand, attest to their compact conformation. A similar transition to more compact dendrimers has recently been shown in a direct comparison of linear and dendritic poly(benzyl ethers) [75]. 

Fig. 5. Dependence of the hydrodynamic radius of poly(benzyl ether) dendrimers on molecular weight Q monodendron tridendron data on low MW polystyrene (A) in a good solvent are included for comparison...

Poly(amidoamine)-(PAMAM-Starburst)-Monodendrons Among the first Starburst (Cascade) syntheses we performed in the early 1980s [83] involved partially masked (differentiated) initiator cores. For example dodecyl-amine, hydroxyalkyl amines or partially protected alkylene diamines were used as initiator cores and submitted to sequential (a) Michael addition with methyl acrylate followed by (b) reaction with an excess of ethylene diamine to give in situ branch cell construction in a divergent manner. The resulting products were core functionalized monodendrons as shown below ... 

Lyotropic liquid crystalline properties were observed for poly (arylamide) monodendrons derived from 1,3,5-substituted amino acid chloride hydrochlorides according to Kim [168]. These systems aggregate readily to form high molecular weight species in the absence of complexing ions. Amide solvents containing more than 40 wt.% of the dendrons exhibit nematic phase liquid crystalline texture under a polarizing microscope, whereas, 60 wt.% solutions produce a hard gel under static conditions. 

Fig. 26. An octameric multiple antigen peptide grafted to the surface of a poly(lysine) monodendron...

Figure 2. Structures of some commonly known dendrimers A. Polyamidoamine (G2) B. Poly(propylene imine) (G4) C. Benzyl ether monodendron (G3) and D. Poly(phenylene) dendrimer (G2). (G represents the generation number)...

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