Polacrilin

Type II diabetes Stimulating the release of insulin from the pancreas. ATP-dependent K-channel blocker Calcium hydrogen phosphate, MCC, maize starch, polacrilin, potassium, povidone, glycerol (85%), magnesium stearate, meglumine, poloxamer Novo Nordisk... 

Alesse -28 Lenonorgestrel and ethinyl estradiol 0.10mg/0.02 mg Tablet Oral contraceptives Estrogen / progestin receptor Cellulose, hypromellose, lactose, magnesium stearate, polacrilin potassium Wyeth... 

For many years, starch was the disintegrating agent of choice. Recently, however, so-called super disinte-grants have been introduced, which markedly reduce tablet disintegration time. Such substances include croscarmellose, crospovidone, polacrilin potassium, and sodium starch glycolate. ... 

Polacrilin potassium 2-10 Cation exchange resin (Amberlite IRP88 )... 

Polacrilin resins are also used in the analysis and manufacture of pharmaceuticals and food products. 

Polacrilin potassium occurs as a cream-colored, odorless and tasteless, free-flowing powder. Aqueous dispersions have a bitter taste. 

Figure 1 Particle size distribution of polacrilin potassium (Amberlite IRP-88).

Solubility practically insoluble in water and most other liquids, although polacrilin resins swell rapidly when wetted. 

Polacrilin potassium and other polacrilin resins are stable to light, air, and heat up to their maximum operation temperature see Table II. Excessive heating can cause thermal decomposition of the resins and may yield one or more oxides of carbon, nitrogen, sulfur, and/or amines. 

Polacrilin resins should be stored in well-closed containers in a cool, dry place. 

Incompatible with strong oxidizing agents, amines, particularly tertiary amines, and some other substances that interact with polacrilin resins. ... 

Polacrilin resin (Amberlite IRP-64) is prepared by the copolymerization of methacrylic acid with divinylbenzene (DVB). Polacrilin potassium (Amberlite IRP-88) is then produced by neutralizing this resin with potassium hydroxide. 

Polacrilin potassium and other polacrilin resins are used in oral pharmaceutical formulations and are generally regarded as nontoxic and nonirritant materials. However, excessive ingestion of polacrilin resins may disturb the electrolyte balance of the body. 

Observe normal precautions appropriate to the circumstances and quantity of material handled. Polacrilin potassium may be irritating to the eyes eye protection and gloves are recommended. 

A number of other polacrilin (Amberlite) resins are commercially available that have a variety of industrial and pharmaceutical applications see Table II. 

Methacrylic acid, 2-phenoxyethyl ester. See 2-Phenoxyethyl methacrylate Methacrylic acid polymer with divinyl benzene, potassium salt. See Polacrilin potassium Methacrylic acid, tetrahydrofurfuryl ester. See Tetrahydrofurfuryl methacrylate Methacrylic acid, 3-(trimethoxysilyl) propyl ester. See3-... 

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