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Podophyllum peltatum Peltatin, Podophyllotoxin

The resin prepared from the dried rhizome and roots of Podophyllum peltatum contains podophyllotoxin, a-pelta-tin, and P-peltatin. When apphed topically, it is a strong irritant to the skin and mucous membranes and can lead to poisoning because of systemic absorption. When taken by mouth, it has a drastic laxative action and produces violent peristalsis. Ingestion of large doses can result in... [Pg.2879]

Podophyllum resin, an alcoholic extract of Podophyllum peltatum, commonly known as mandrake root or May apple, is used in the treatment of condyloma acuminatum and other verrucae. It is a mixture of podophyllotoxin, and peltatin, desoxypodophyllotoxin, dehydropodophyllotoxin, and other compounds. It is soluble in alcohol, ether, chloroform, and compound tincture of benzoin. [Pg.1303]

Podophylli rhizoma Podophyllum May apple. Mandrake root Podophyllum peltatum L. Berberidaceae 3%-6% resin (--lb compounds) with 0.2%-l% podophyllotoxin and the p-D-glucoside a-, p-peltatine and their p-D-glucosides Picropodophyllin (an artefact due to extraction procedures) Kg. 5... [Pg.265]


See other pages where Podophyllum peltatum Peltatin, Podophyllotoxin is mentioned: [Pg.3]    [Pg.117]   


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