Pleasure ratings

It is my pleasure to introduce Volume 50 of Annual Reports on NMR Spectroscopy. The present volume contains first rate contributions on diverse areas of molecular science, and I am deeply indebted to the authors for their fascinating accounts and for the prompt delivery of their manuscripts. 

In 1996 the FDA approved the antidepressant bupro-prion (Zyban) for the treatment of nicotine dependence. This sustained-release pill blocks nicotine s pleasurable effects and helps to maintain abstinence whether the user has depression or not. The length of suggested use is for seven to 12 weeks, including one to two weeks before quitting tobacco. Buproprion doubles the quit rate and has been demonstrated to be safe when used jointly with NRT. 

The CNS includes the spinal cord (which deals with basic reflexes, walking movements, and control of information to and from the brain), the subcortical brain (which deals with such matters as coordination balance and equilibrium wakefulness respiration and heart rate and basic emotions such as anger, excitement, sexual response, and response to pain and pleasure), and the cerebral cortex (which receives sensory input controls motor functions and deals with higher functions of thinking, memory, integration of information, learning, and executive function (see Figure 1.4). 

As we have noted, the set of reaction rates which interconnect various chemical species are the most important properties in any catalytic experience, or investigation it is a pleasure therefore to devote a large section (J. Wei and C. D. Prater) to notable advances in the analysis and interpretation of measured transformation rates in terms of the actual individual reaction rate parameters between transforming species... 

Rush, Roll, Higgins, 1998). The combination of cocaine (or amphetamine) and heroin (or other opiate) is called a speedbair and is particularly popular among heroin addicts. Morphine and cocaine combinations have been studied in the laboratory, and as with alcohol, morphine appeared to enhance the pleasurable effects of cocaine but also increased the cardiovascular effects. Combinations of cocaine and heroin have sometimes been blamed for drug overdose deaths (as in the deaths of comedian John Belushi and actor River Phoenix), and the synergistic effects on blood pressure and heart rate may be a factor (Foltin Fischman, 1992 Rush et al., 1998). 

MDMA causes a feeling of clarity or sharpness, tingling, pleasure, and a feeling of disassociation. It can result in dehydration, seizures, hyperthermia, tachycardia, and renal impairment. LSD is also a hallucinogen but does not have an amphetamine component. The drug causes visual hallucinations. Emotions can be labile and paranoia can occur. Increased body temperature, heart rate, and blood pressure can occur. Some people experience flash-backs. 

Among the pleasures afforded us in viewing a first-rate narrative film or video are a kind of automatic deciphering of possible subtext along with an appreciation (the more conscious, the more pleasurable) of the tension that exists between text and subtext. 

Reading Rate The speed at which a selection is read and the manner in which it is read, depending on the purpose skimming, scanning, studying, or reading for pleasure. 

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