Planar patch

There are currently two main types of plate-based planar patch instmments those which produce giga-Ohm seals, as in conventional patch clamp (e.g., PatdiXpress, QPatch) and those producing <100mega-Ohm seals as a compromise to allow a higher throughput (e.g., lonWorks HT, lonWorks Quattro) [57, 58]. [Pg.394]

The solid angle of a planar patch with area Aobj at a distance r from the origin is calculated as... [Pg.48]

Figure 3.12 The irradiance falling onto a planar patch is reduced by a factor of cost , where 9 is the angle between the direction of the light source and the normal vector of the planar patch.

Let L be the radiance given of by a light source. The irradiance falling on a planar patch depends on the angle 9 between the normal vector of the patch and the direction of the fight source as shown in Figure 3.12. Let Nobj be the normal vector of the patch and let Nz, be the normal vector that points to the direction of the fight source. Then the... [Pg.49]

Let E(9, takes care of the fact that the irradiance is reduced by cos 6 if it falls on the patch at an angle. We integrate over all infinitesimal patches of the hemisphere. [Pg.54]

Various surface thermodynamic considerations relevant to supported metal catalysts are presented. They include the thermodynamics of (1) spreading of the active catalyst on the support, (2) crystallite vs. film stability, (3) thin planar patches, (4) the phase separation on the substrate, and (5) the rupture of thin films. These thermodynamic considerations explain a number of phenomena observed during experiments with model catalysts. [Pg.33]

Patch clamp Planar patch Screening technologies... [Pg.3]

Conventional Patch Planar Patch Flip-the-Tip Patch... [Pg.9]

Recent development of the planar patch technique has allowed the development of high throughput electrophysiology. The planar patch clamp process... [Pg.16]

Now part of MDS Analytical Technologies Planar patch glass sealchip GS2 seal overall, low... [Pg.17]

Ballerup, Denmark Planar patch QPlate preparation facility ... [Pg.17]

Munich, Germany Planar patch borosilicate intracellular ... [Pg.18]

Behrends JC, Fertig N (2002) Planar patch clamping. In Walz W (ed) Neuromethods, vol 38 Patch-damp analysis, 2nd edn. Humana, New Jersey, p 411... [Pg.25]

Xu, J. et al. 2003. A benchmark study with SealChip planar patch-clamp technology. Assay Drug Dev. Technol. 1, 675-684. [Pg.82]

APCC automated planar patch clamp, cFPD local field potential, FABP3 cardiac fatty acid-binding protein, PPCIW population patch clamp by IonWorks Quattro, VC voltage clamp... [Pg.53]

Milligan CJ, Li J, Sukumar P et al (2009) Robotic multiwell planar patch-clamp for native and primary mammalian cells. Nat Protoc 4(2) 244-255... [Pg.73]

N = 194 uncharged hERG blockers planar patch clamping data IC5o< lOpM... [Pg.319]

See Patch-Clamp Analysis Advanced Techniques, Walz, W., Boulton, A.A., Baker, G.B., Eds. (Totowa, NJ, Humana Press, 2002). See also Behrends, J.C., Fertig, N. Planar Patch Clamping, available at www.nanion.de/ pdf/PlanarPatchClamping.pdf. [Pg.467]

The on-chip-based patch clamp technique broadens the possibilities of ion channel analysis by transferring the classic patch clamp principle onto a microstructured chip format. The planar patch clamp technique enables the automation and parallelization of ion charmel measurements. This is an example of the beneficial integration of microtechnological processes in the field of... [Pg.2683]

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