Pitocin - Oxytocin

Paregoric Opium Tincture (lauda- Pitocin Oxytocin... 

Oxytocin (Pitocin, Syntocinon) causes milk release (letdown) by stimulating contraction of the myoepithelial cells of the milk ducts in lactating mammary glands this forces milk from the alveoli of the breast. Oxytocin release is stimulated by suckling and by auditory and visual stimuli, such as a baby s cry. Oxytocin is available as a nasal spray, which is used as an aid to lactation when milk ejection is impaired. 

Oxytocin (Pitocin, Syntocinon) is a cyclic 8-amino acid peptide that is synthesized in the paraventricular nucleus of the hypothalamus and transported within hypothalamic neurons (in association with neurophysin) to the posterior pituitary for storage. Its mechanism of action involves the direct stimulation of oxytocin receptors found on the myometrial cells. Oxytocin circulates unbound in the plasma, where it has a half-Ufe of approximately 15 minutes. It is primarily inactivated in the kidneys and liver. 

Oxytocin is used in induction of labour, in postpartum haemorrhage, abortion and in breast engorgement. It is used by IM/IV route (PITOCIN, 2-5 lU/ml inj). 

Manufacturers Monarch Pharmaceuticals, Bristol, TN (Pitocin) Wyeth-Ayerst, Philadelphia, PA (Oxytocin for Injection) Eon Labs, Laurelton, NY (Oxytocin Solution for Injection) Fujisawa, Deerfield, IL (Oxytocin Solution for Injection)... 

Dosage form Pitocin is available in a 1 ml ampule, a 1 ml prefilled syringe, a 1 ml vial, and a 10ml multiple-dose vial. Each preparation contains oxytocin 10 units/ml. Oxytocin Solution for Injection (Eon, Fujisawa) is supplied as a 1 ml ampule or vial and a 10 ml vial each contains oxytocin 10 units/ml. Oxytocin for injection also contains oxytocin 10 units/ml. 

Oxytocin Pitocin , Syntocinon Phentolamine Regitin , Rogitin ... 

Dawood, M.Y. Ylikorkala, O. Fuchs, F. Plasma oxytocin levels and disappearance rate after buccal pitocin. Am. J. 

Once the cervix has been ripened, or in patients who present with a favorable, soft cervix, labor induction can proceed with IV oxytocin (Pitocin ). This is a synthesized form of the same peptide composed of nine amino acids that is synthesized by the hypothalamus and secreted by the posterior pituitary. Although it will cause contractions beyond the late second trimester of pregnancy, these contractions do not always lead to labor. Labor also can be initiated or augmented by rupture of the amniotic and chorionic membranes, which is thought to up-regulate oxytocin receptors on the uterus and release prostaglandins. Nipple stimulation causes the increased release of oxytocin from the posterior pituitary and can be used to initiate corrtractions as well. 

Pitocin. See Oxytocin injection Piiiessin. See Va.s( ressin injection Hiressin Tannutc.. r Vasopressin lannate Pituitary amidiuietic hormone. See Vasopressin... 

Oxytocin (e.g., Pitocin) T force and frequency of uterine contractions. Most pronounced in near-term uterus. Contraction of myoepithelium surrounding alveoli of mammary gland. Antidiuretic (vasopressin) effects. Drug of choice to induce or accelerate labor, to decrease postpartum uterine bleeding. Stimulates milk ejection from breast (nasal spray). ... 

The tocolytic oxytocin (Pitocin) to a client with an incomplete abortion. 

Which assessment data would warrant immediate intervention for the client in labor who is receiving an oxytocin (Pitocin) drip, a tocolytic agent ... 

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