Pirbuterol 3-agonist

Levalbuterol nebulizer solution Levalbuterol MDI (45 mcg/puff) Pirbuterol MDI (200 mcg/puff) Systemic /J-agonists... 

One of the first 8-adrenoreceptor agonists used both currently and in the past as a bron-cholytic is epinephrine or adrenaline, isoproterenol, and especially ephedrine. In treatment and prevention of obstructive respiratory tract diseases, other j3-adrenoreceptor agonists also are used, such as isoetharine, terbutaUne, albuterol, metaproterenol, and also those described in this section—fenoterol (23.3.16), pirbuterol (23.3.22), and procaterol (23.3.25). 

Pirbuterol acetate P2 agonist short 600 u,g 1 -2 u,a/ka 5 1-4 Equine Aerosol Delivery Device (Derksen... 

P Adrenergic agonists, such as albuterol, bitolterol, isoproterenol, metaproterenol, pirbuterol, and terbutaline in the inhaled form, have become the treatment of choice for a short-acting approach to relief of asthma. These drugs are very effective at providing rapid bronchodilation without significant cardiac or systemic effects. Because they are administered in the vapor form, have short time of action, and produce little toxicity, measurement of blood levels offers little clinical benefit patient response provides a convenient form of monitoring therapy. 

FIGURE 10.16 In vivo effects of p-adrenoceptor partial agonists of differing intrinsic efficacy. Changes in heart rate (increases in beats/min) shown in anesthetized cats. Chloralose-pentobarbital anesthesia (filled circles) yields low basal heart rates, while urethane-pentobarbital anesthesia (open circles) yields high basal heart rates. Responses to (in order of descending relative intrinsic efficacy) (A) pirbuterol, (B) prenalterol, and (C) pindolol. Redrawn from [50]. 

Pirbuterol, a beta-adrenergic agonist with bronchodilating properties (1 to 2 inhalations every 4 to 6 hours), is indicated in the prevention and reversal of bronchospasm and asthma... 

Pirbuterol is a relatively selective 2 agonist structurally related to albuterol. Pirbuterol acetate (maxair) is available for inhalation therapy dosing is typically every 4-6 hours. 

Beta-2 adrenoceptor agonists Inhaled Short-acting Bitolterol, Clenbuterol, Fenoterol, Levosalbutamol, Pirbuterol, Procaterol, Reproterol, Salbutamol (Albuterol), Terbutaline, Tolubuterol Long-acting Arformoterol, Formoterol, Salmeterol... 

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