Pigment epithelium derived factor

The best match was to mouse pigment epithelium-derived factor precursor (PEDF) (stromal cell-derived factor 3) (SDF-3) 46204.3 Da, pi = 6.48 and accession P97298. 

Becerra SR Sagasti A, Spinella R Notario V Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop. J Biol Chem 1995 270 25992-25999. 

I I Doll JA, Stellmach VM, Bouck NR et al. Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. Nat Med 2003 9 774-780,... 

Activated VEGFR1 alone, however, has relatively weak tyrosine kinase activity and may be insufficient to stimulate endothelial cell proliferation [20]. On the other hand, inhibition of angiogenesis by factors such as pigment epithelium-derived factor (PEDF) is associated with reduced VEGF-induced phosphorylation of VEGFR1 [23],... 

Cai J, Jiang WG, Grant MB, Boulton M. Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1. J Biol Chem 2006 281 3604-3613. 

Dawson DW, Volpert OV, Gillis P, Crawford SE, Xu H, Benedict W, et al. Pigment epithelium-derived factor A potent inhibitor of angiogenesis. Science 1999 285 245-248. 

Osteoblast specific factor-2 Pigment epithelium-derived factor PK-120 (not in databases...) Plasminogen ... 

Tombran-Tink J, Shivaram SM, Chader GJ, Johnson LV, Bok D. 1995. Expression, secretion, and age-related down-regulation of pigment epithelium-derived factor, a serpin with neurotrophic activity. J Neurosci 15 4992-5003. 

Duh EJ, Yang HS, Suzuma I, et al. Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth. Invest Ophthalmol Vis Sci 2002 43 821-829. 

Mori K, Duh E, Gehlbach P, et al. Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization. J Cell Physiol 2001 188 253-263. 

Mori K, Gehlbach P, Yamamoto S, et al. AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Invest Ophthalmol Vis Sci 2002 43 1994-2000. 

Raisler BJ, Berns KI, Grant MB, Beliaev D, Hauswirth WW. Adeno-associated virus type-2 expression of pigmented epithelium- derived factor or Kringles 1-3 of angiostatin reduce retinal neovascularization. Proc Natl Acad Sci USA 2002 99 8909-8914. 

Kenchegowda, S., J. He et al. 2013. Involvement of pigment epithelium-derived factor, doco-sahexaenoic acid and neuroprotectin D1 in corneal inflammation and nerve integrity after refractive surgery. Prostaelandins Leukot. Esse.nt. Fatty Acids 88(11 27-31. 

Doxorubidn and gene encoding pigment epithelium-derived factor... 

Ta, H. T., Dass, C. R., Larson, L, Choong, P. F. M., and Dunstan, D. E. 2009b. A chitosan hydrogel dehvery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy. Biomaterials, doi 10.1016/j.biomaterials.2009.05.035. 

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