Pi stacking

Haining, R. L., Jones, J. R, Henne, K. R., et al. (1999) Enzymatic determinants of the substrate specificity of CYP2C9 role of B -C loop residues in providing the pi-stacking anchor site for warfarin binding. Biochemistry 38, 3285-3292. 

Pi-stacking and electron donor-acceptor interactions have also been extensively used for designing host-guest complexes in a predictable manner [8]. 

Warman JM, de Haas MP, Dicker G, Grozema FC, Piris J, Debije MG. (2004) Charge mobilities in organic semiconducting materials determined by pulse-radiolysis time-resolved microwave conductivity Pi-bond-conjugated polymers versus pi-pi-stacked discotics. Chem Mater 16 4600-4609. 

Hall DB, Barton JK. Sensitivity of DNA-mediated electron transfer to the intervening pi-stack a probe for the integrity of the DNA base stack. J. Am. Chem. Soc. 1997 119 5045-5046. 

N. (2004) Environmental fluctuabons fadlitate electron-hole transfer from guanine to adenine in DNA pi stacks. Angewandte Chernie International Edition, 43, 624-627. 

Gazit, E. (2002) A possible role for pi-stacking in the self-assembly of amyloid fibrils. EASES J, 16, 77-83. 

Pi-pi stacking interactions (183-185) An interaction between two aromatic groups arising from numerous forces, primary of which are attractive van der Waals forces. There are also contributions from electrostatics, induction, and exchange-repulsion. 

This interaction orients the rest of the diketopiperazine core toward the mobile H-loop where it forms a pi-stacking interaction above and below the plane of the ring with Phe786 and Phe820, respectively. The interaction with Gln817 orients the benzodioxol substituent into the same hydrophobic pocket utilized by the ethoxyphenyl of sildenafil and vardenafil. A recent review of the SAR of a large number of PDE5 inhibitors from... 

Based on the characteristic features of these bands, we assigned them to monomer, J-like aggregates and pi-pi stacking aggregates. The change of the H2O2 production curve is well correlated to the status of the porphyrin in the solution as shown in Fig.2. CP showed quite similar result as UP. 

Li, X.C. et ah, A highly pi-stacked organic semiconductor for thin film transistors based... 

Pappenfus, T.M. et al., A pi-stacking terthiophene-based quinodimethane is an n-channel... 

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