Physiological fluids, Automated analysis

J. A. Vinson, J. J. Urash, and D. J. Lopatofsky, A semi-automated extraction and spotting system for the analysis of drugs in physiological fluids. In Analytical Methods in Forensic Chemistry (M. H. Ho, ed.), Ellis Horwood, New York, 1990, p. 385. 

The past decade has witnessed a proliferation of methods and media for direct injection of physiological fluids into HPLC systems. The numerous studies and apphcations of the principle of direct injection clearly demonstrate that the technique now has matured to a stage where it can be used routinely in bioanalytical laboratories, for the automated analysis of a large number of samples [1]. 

Automated Analysis of the Volatile Condtituents of Physiological Fluids with Glass Capillary Column Gas Chtomatography and Pattern Recognition Techniques Univ. Microfilms Int., Order Bo. 1977-22,665, 221 pp. Diss. Abstr. Int. 38B(5) 2149 CA 88 34007q... 

Automated Qualitative and Quantitative Analysis of GC/MS Data of Complex Mixtures from Physiological Fluids... 

Quantitative methods for analyzing for large numbers of the individual constituents of body fluids have frequently involved several steps and excessive operator time. As a result, such complex analyses have been relegated to the research laboratory. It would be extremely difficult and expensive for the clinical laboratory to use these methods on a routine basis, even if they could be entirely automated. However, new high-resolution analytical systems that are capable of automatically analyzing for many of the individual constituents of a physiological sample may be useful in the clinical laboratory for such an in-depth analysis. 

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