Phototoxicity Toward Bacteria and Fungi

It has been tempting to derive quantitative or qualitative conclusions on relative phototoxicity by measuring the diameters of zones of inhibition produced by different compounds under identical conditions. It is 

In addition to Tl, 1,6 and 7 were also proved phototoxic to E. coli as well as S. cerevisiae 98, 183, 184). 

The relatively small number of microorganisms in which the toxicity of bi- and trithiophenes has been observed forbids extrapolation of the results to other microorganisms with much confidence. Two studies concluded that neither Pseudomonas aeroginosa nor P. fluorescens were affected by a-terthienyl, either aerobically or anaerobically (178, 238). A third study, however, reported this compound, along with 1, 6, and 7, to be phototoxic to P. aeroginosa (98). Both 1 and T1 had the same level of phototoxicity, a level which was greater than for the other two com- 

Verticillium species) were not affected by cercosporin. Daub s work also confirmed that the presence of carotenoids and the composition of the cell wall were important in conferring resistance to organisms, in this case to fungi. 

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