Phosgene long-term effects

Most of the materials used in the manufacture of chemicals are poisonous, to some extent. The potential hazard will depend on the inherent toxicity of the material and the frequency and duration of any exposure. It is usual to distinguish between the short-term effects (acute) and the long-term effects (chronic). A highly toxic material that causes immediate injury, such as phosgene or chlorine, would be classified as a safety hazard. Whereas a material whose effect was only apparent after long exposure at low concentrations, for instance, carcinogenic materials, such as vinyl chloride, would be classified as industrial... 

No in vitro toxicity studies have been reported. The mechanism of phosgene oxime toxicity is unknown and long-term exposure effects have not been determined. 

The effects of long-term exposure to phosgene oxime in humans are not known. 

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