Phenylmethyl amine

Chemical Designations - Synonyms Alpha-Aminotoluene, Phenylmethyl Amine Chemical Formula C HjCH NH. ... 

Phenylhydrazine Hydrochloride Phenylhydrazinium Chloride Phenyl Hydroxide Phenylmethanol Phenylmethyl Alcohol Phenylmethyl Amine Phenylphosphine Dichloride Phenylphosphine Thiodichloride Phenylphosphonothioic Dichloride Phenyl Phosphonous Dichloride Phenylpropylene 1 -Phenyltetradecane 1-Phenylundecane Phosgene Phosphoric Acid Phosphoric Sulfide... 

PHENYLMETHYL AMINE (100-46-9) A strongly alkaline liquid. Incompatible with strong acids, organic anhydrides, isocyanates, aldehydes, alkylene oxides, epichlorohydrin, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Violent or explosive reaction with A-chlorosuccinimide. Slowly corrodes some metals. Attacks some plastics, rubber, and coatings. 

CAS 100-46-9 EINECS/ELINCS 202-854-1 Synonyms Aminotoluene a-Aminotoluene Benzylamine Monobenzylamine (Phenylmethyl) amine... 

Phenylmethyl alcohol. See Benzyl alcohol (Phenylmethyl) amine. See N-Benzylamine N-Phenylmethylamine. See N-Methylaniline Phenylmethyl benzoate. See Benzyl benzoate... 

Phenyl Hydroxide Phenylmethanol Phenylmethyl Alcohol Phenylmethyl Amine Phenylphosphine Dichloride... 

C23H3g03Si 152185-73-4) see Docetaxel trisodiuin thiophosphate dodecahydrate (H24Na30isPS 51674-17-0) see Amifostine [S-(/f 4 )]-A,A, a-tris(phenylmethyl)oxiranemcthan-amine... 

Nicardipine Nicardipine, l,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-methyl-2-[(methyl-phenylmethyl)-amino]ethyl ester 3,5-pirididincarboxylic acid (19.3.7), is synthesized in a manner analogous to the synthesis of nifedipine, the only difference being that in the Hantsch synthesis, two different )3-dicarbonyl compounds are used simultaneously with o-nitrobenzaldehyde. During this, one of these in the enamine form of acetoacetic ester is simultaneously used as an amine component. A heterocycUzation reaction is accomplished by reacting, the methyl ester of 8-aminocrotonic acid with the 2-methyl-2-benzyl-aminoethyl ester of acetoacetic acid [24-27]. 

TRIFLUOROPHENYL)BORONIC ACID-CATALYZED AMIDE FORMATION FROM CARBOXYLIC ACIDS AND AMINES N-BENZYL-4-PHENYLBUTYRAMIDE [Benzenebutanamide, N-(phenylmethyl)-]... 

Stepwise Selective Amine and Amide Alkylation (Fig. 14) 44 A first alkylation step is performed by suspending (78) in a 2 M solution of a suitable alkyl halide in DMF at 50° for 24-48 h. After thorough washing with DMF (3x), CH2C12 (3x), and THF (3x) intermediate (79) (usually formed with >85% purity) is subjected to the final alkylation. The reaction flask is sealed with a fresh rubber septum and flushed with nitrogen followed by cooling to 0°. In a separate flame-dried 25-ml round-bottom flask 12 equiv. (with respect to 79) of 5-phenylmethyl-2-oxazolidinone is added. To the reaction flask freshly distilled THF is added (the appropriate volume to provide a 0.2 M solution of the 5-phenylmethyl-2-oxazolidi-none). The resulting clear solution is then cooled to —78° and 1.6 M n-butyl... 

Chemical Name lH-Benzimidazol-2-amine, 6-((E)-(hydroxyimino) phenylmethyl)-l-((l-methylethyl)sulfonyl)-... 

Chiral glycine enolate synthons have been employed in diastereoselective alkylation reactions [15]. A complementary approach to the synthesis of a-amino acids is the electrophilic amination of chiral enolates developed by Evans [16]. Lithium enolates derived from A-acyloxazolidinones 38, reacted readily with DTBAD to produce the hydrazide adducts 39 in excellent yields and diastereoselectivities (Scheme 18). Carboximides 38 were obtained by A-acylation of (S)-4-(phenylmethyl)-2-oxazoli-dinone and the lithium-Z-enolates of 38 were generated at -78 °C in THF under inert atmosphere using a freshly prepared solution of lithium diisopropylamide (LDA, 1.05 equiv.) [17]. 

C28H28N4 157875-56-4) see Imiquimod Y4-(2-methylpropyl)-Ar2,Ar2-bis(phenylmethyl)-2,3,4-quino-linetri amine... 

Polymer-immobilised catalysts containing gold particles smaller than 10 nm have been prepared by impregnating Merck Ion Exchanger IV with HAuCU, and have been used to synthesise ureas and carbamates by reaction of amines with carbon monoxide and oxygen 16 so for example the oxycarbonylation of aniline proceeded at 448 K and 5 MPa pressure (C0 02 = 2 l) in 1-3 h to give yields of up to 99% of phenylmethyl-carbamate (Scheme 13.3). 

N-(2,6-DIMETHYLPHENYL)-N-(METHOXYACETYL)-DL-ALANINE METHYL ESTER see MDMIOO N,N-DIMETHYL-3((1-PHENYLMETHYL)-1H-INDAZOL-3-YL)OXY-l-PROPAN AMINE HYDROCHLORIDE see BBW500 N-(2,6-DIMETHYLPHENYL)-l-METHYL-2-... 

The polymerization of cyclic sulfides and amines provided, although tentatively, some information on kp and kp. The equality k kp was found (the Kq value measured for an initiator used was further applied in the determimtion of a in polymerization studies) in the polymerization of 3,3-dimethylthietane in CgHsNOa and qualitatively for l-phenylmethyl-2-methyl-aziridine Small differences were found between kp and k (the macrocation being less... 

Allyl- (25) and phenacyl-amines (26) are also practical alternatives. They can be cleaved after isomerization of the allyl moiety to the acid sensitive vinyl amines, or with zinc in acetic acid. The bulky tri-phenylmethyl (Tr) group (27), readily removed by mild acid hydrolysis, possesses advantageous shielding properties and has found applications in the protection of amino acids (Scheme 16). ... 

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