Alanine methyl ester

N-(tert-Butoxycarbonyl)-P-4-(methoxycarbonyl)phenyl]alanine methyl ester L-Phenylalanine, N-[(l,l-dimethylethoxy)carbonyl]-4-(methoxycarbonyl)-, methyl ester (160168-19-4)... 

No compound other than the methyl ester of N-benzoyl-Lphenylalanine, 33, is an obvious choice for an open-chain analog of the locked substrate 25 but D-24, on the other hand, may be a locked analog of either N-benzoyl-D-alanine methyl ester 34 or of N-formyl-D-phenylalanine methyl ester 35 (75). If 24 is an analog of 34 rather than 35, the comparison of the two locked analogs made in Section V.B. is not valid the phenyl of 24 would then correspond to the benzoyl phenyl of 34. 

N-[N-(benzyloxycarbonyI)-L-prolyl-L-aspart-4-oyl]-N-[N-(benzyloxycarbonyl)-L-seryl-L-aspart-l-oyl-(L-alanine methyl ester)-4-oyl]-... 

N-[N-(benzyloxycarbonyl)-L-aspart-l-oyl-(L-alanyl-L-threonyl-L-leucyl-L-alanyl-L-serine)-4-oyl]-N-(N-(benzyloxycarbonyl)glycyl-L-aspart-4-oyl]-N-[N-(benzyloxycarbonyl)-L-leucyl-L-aspart-4-oyl]-N-[N-(benzyloxycarbonyl)-L-prolyl-L-aspart-4-oylJ-N-[N-(benzyloxycarbonyl)-L-tyrosyl-L-aspart-4-oyl]-N-[N-(benzyloxycarbonyl)-L-valyl-L-aspart-4-oyl -N-(lert-butoxycarbonyl)-L-aspart-1 -oyl-(L-phenylalanyl-L-alanine methyl ester)-... 

N-(terf-butoxycarbonyl)-N-(tert-butoxycarbonyl)-, benzyl ester glycyl-L-alanine-, methyl ester... 

L-phenylalanyl L-phenylalanine methyl ester L-prolyl L-alanine methyl ester L-prolyl L-aspartic dibenzyl ester L-prolyl glycine ethyl ester L-prolyl methyl ester L-serylglycine ethyl ester... 

L-alanyl-L-alanine methyl ester L-alanylglycine ethyl ester... 

L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophanyl-L-lysyl-L-threonyl-L-threonyl-L-cysteine 6-0-benzoyl-N-(benzyloxycarbonyl) methylamide 4,6-0-benzylidene-N-benzylidene-N-(benzyloxycarbonyl) methylamide N- (benzyloxy carbonyl) -N-(benzyloxycarbonyl)-, amide N-(benzyloxycarbonyl)-, hydrazide N-(benzyloxycarbonyl)-, methylamide N-(benzyloxycarbonyl)-, methyl ester N-(benzyloxycarbonyl)-L-alanyl-L-alanine methyl ester N-(benzyloxycarbonyl)-L-alanylglycine ethyl ester N-(benzyloxycarbonyl)glycyl-L-alanine methyl ester 3,4,6-tri-0-acetyl-2-amino-2-deoxy-N-(benzyloxycarbonyl)-, benzyl ester, hydrochloride... 

The instability of these chiral monolayers may be a reflection of the relative stabilities of their bulk crystalline forms. When deposited on a clean water surface at 25°C, neither the racemic nor enantiomeric crystals of the tryptophan, tyrosine, or alanine methyl ester surfactants generate a detectable surface pressure, indicating that the most energetically favorable situation for the interfacial/crystal system is one in which the internal energy of the bulk crystal is lower than that of the film at the air-water interface. Only the racemic form of JV-stearoylserine methyl ester has a detectable equilibrium spreading pressure (2.6 0.3dyncm 1). Conversely, neither of its enantiomeric forms will spread spontaneously from the crystal at this temperature. 

Protonated imines are effective dienophiles. Thus in the reaction of methyl glyoxylate with the hydrochloride 127 of alanine methyl ester in the presence of cyclopentadiene, a mixture of hydrochlorides of the exo- and ewrfo-adducts 128-131 was formed (equation 69). The diastereomeric ratio of the exo-compounds was 83 1761. 

Oxidation of 4-methoxycatechol with Ag20 in the presence of /3-alanine methyl ester resulted in the formation of a complex mixture from which compound 57 was isolated in 0.4% yield (82HCA1279). 

Oxidation of catechol with Ag20 in presence of /3-alanine methyl ester gave a phenoxazine-2,3-dione in low yield, and further condensation with o-phenylenediamine gave the pentacyclic compound 153 [78ZN(C)912],... 

The principles of the method are very nicely illustrated by one of the first affinity labeling experiments, the reaction of /exs-i.-phenylalanine chloro-methyl ketone (TPCK) with chymotrypsin.1 TPCK resembles substrates like fexs-L-pheny 1 alanine methyl ester, but the chloromethyl ketone group of TPCK is an alkylating reagent. 

Wulff and his collaborators reported, in 1989, the preparation of imprinted polymers able to perform enantioselective synthesis [11, 12]. The imprinting complex was prepared by reacting 3,4-di-hydroxy-phenyl-alanine methyl-ester (l-DOPA methyl ester) (16) with the 4-vinyl-salicylaldehyde (17) to form the corresponding Schiff s base (18), which was further reacted with the 4-vinyl-phenyl-boronic acid (19) to afford to the corresponding ester (20) (Scheme 4). The imprinting complex obtained was then polymerised and the template removed. The resulting polymers were incubated with sodium glycinate to allow formation... 

MAP (2,4-dinitrophenyl-(1)-alanine methyl ester) (44,45) is a comparatively older material which crystallizes on slow cooling from 34% ethyl acetate/hexane solutions over about three weeks as 0.2 cm3 monoclinic crystals (A = 6.829 A, b = 11.121 A, c = 8.116 A, b = 95.59°), mp 80.9° C. The yellow-orange crystals are transparent from about 500 nm to 2.0 11 at... 

Dihydro-2//-pyrido[l,2-a]pyrimidin-2-one 261 was prepared in 42% yield when dinitrile 260 was reacted with /3-alanine methyl ester hydrochloride (90EGP279020). 

K. Oyama, K. Kihara, and Y. Nonaka, On the mechanism of the action of thermolysin kinetic study of the thermolysin-catalyzed condensation reaction of N-benzyloxy-carbonyl-t-aspartic add with L-phenyl-alanine methyl ester, J. Chem. Soc. Perkin Trans. 2 1981a, 356-360. 

Fig.4 The principle of chiral recognition by gas sensors chiral discrimination by preferential sorption of the enantiomers of N-TFA-alanine methyl ester (N-TFA-Ala-OMe) into enantioselective (R)- and (S)-octyl-Chirasil-Val polymers. The chemical information is transformed into optical signals by the respective transducers...

Chemical Name N-(((2RS,4R)-2-Methyl-4-thiazolidinyl)carbonyl)-p-alanine, methyl ester... 

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