Phascolopsis gouldii

FIGURE 6.46 The oligomeric states of hemerythrin in various marine worms, (a) The hemerythrin in Thermkte zostericola crystallized as a monomer (b) the octameric hemerythrin crystallized from Phascolopsis gouldii (c) the trimeric hemerythrin crystallized from Sipiwnosoma collected in mangrove swamps in Fiji. 

The structures are known for the octamer from Phascolopsis gouldii and Themiste dyscritum (33, 34). The eight identical subunits are packed as a "square donut" with four subunits in each of two layers. The binuclear iron units are at corners of an almost regular square antiprism with distances of 2.8-3.0 nm between adjacent binuclear iron centers. The disproportionation... 

Figure 10.2. Amino acid seqnence alignment of D. vulgaris HUdenborongh DcrH residues 824-959 (top) with Phascolopsis gouldii Hr (bottom). Letters indicate residues that are common to both sequences, which are also conserved in all known Hr sequences boldface indicates residues furnishing iron ligands in Hr. Reprinted with permission from Xiong et al. (2000), copyright 2000 American Chemical Society.

Figure 17 UV-vis absorption spectra of oxy and deoxyHrs from Phascolopsis gouldii.

Nocek JM, Kurtz Jr DM, Sage JT, Debrunner PG, Maroney MJ, Que Jr L. 1985. Nitric-oxide adduct of the binuclear iron center in deoxyhemerythrin from Phascolopsis gouldii analog of a putative intermediate in the oxygenation reaction. J Am Chem Soc 107 3382-3384. 

Farmer CS, Kurtz DM, Liu ZJ, Wang BC, Rose J, Ai JY, Sanders-Loehr J. 2001. The crystal structures of Phascolopsis gouldii wild type and L98Y methemerythrins structural and functional alterations of the O2 binding pocket. J Biol Inorg Chem 6 418-429. 

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