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Pharmacological response variation

As is apparent from the literature reviewed above, that culture and ethnicity are powerful determinants of an individual s response to psychopharmacotherapy. Progress in this regard will vastly improve our current practice in using medications. However, it is necessary to remember that there are often very substantial inter-individual variations within any defined cultural or ethnic group, and that ethnic variations in pharmacological responses should not be interpreted stereotypically. [Pg.34]

The same story plays out for the toxicity and efficacy of drugs, where a number of examples of a role for genetic variation in pharmacologic response... [Pg.45]

Pharmacokinetic modeling, 208 Pharmacokinetics (PK), 99, 211 Pharmacologic agents, variation in response to, 43 Pharmacologic research, 31 Pharmacology, genetic variation and, 36-38... [Pg.360]

C-ring variations have by far the most significant influence on pharmacological responses in these series. [Pg.80]

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