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Pharmacogenomics personalized medicine

Overall, by using the principles of pharmacogenomics, personalized medicine, and pharmacotyping in patient care, and by monitoring their impact on current drug development and delivery, a major benefit is expected upon co-evaluation of... [Pg.202]

Key Words Pharmacogenetics pharmacogenomics personalized medicine populations gene expression drug targets. [Pg.3]

Silber BM. Pharmacogenomics, biomarkers, and the promise of personalized medicine. In Pharmacogenomics (Ka-low W, Meyer UA, Tyndale RF, Eds.). New York, Basel Marcel Dekker 2001 11-31. [Pg.9]

Jain, K.K., Role of pharmacogenomics in the development of personalized medicine, Pharmacogenomics 5, 331-336, 2004. [Pg.28]

Sullivan, C. G. 2004. How Personalized Medicine is Changing the Rules of Drug Life Exclusivity. Pharmacogenomics 5 429-432. [Pg.105]

A notable application of pharmacogenomics in early phase drug development, which extends beyond personalized medicine, is in proof-of-concept investigations. Phase 2A/2B trials enriched for patients with certain genetic subtypes of drug targets previously shown to confer an increased likelihood of response can facilitate decisions on whether and to what extent a NME is a viable therapeutic candidate. Conversely, an inadequate response to a NME in such enriched samples may serve as an early indication of possible therapeutic failure in the general patient population. [Pg.32]

No author listed]. Bulletin Board Study finds overwhelming majority of American consumers and physicians back development of personalized medicine. Pharmacogenomics 2003 4 13. [Pg.48]

Sanders R. Molecular diagnostics and personalized medicine. Pharmacogenomics 2003 4 541-545. [Pg.49]

Mancinelli L, Cronin M, Sadee W. Pharmacogenomics the promise of personalized medicine. AAPS PharmSci 2000 2(1) E4. [Pg.84]

Emergence, Nonlinearity, Personalized medicine, Pharmacogenomics, Systems biology, Systems... [Pg.3]

Samwald M, Coulet A, Huerga I et al (2012) Semantically enabling pharmacogenomic data for the realization of personalized medicine. Pharmacogenomics 13 201-212... [Pg.34]

Whirl-Carrillo M, McDonagh EM, Hebert JM, Gong L, Sangkuhl K, Thorn CF, Altman RB, Klein TE (2012) Pharmacogenomics knowledge for personalized medicine. Clin Pharmacol Ther 92(4) 414-417... [Pg.90]

Key words Pharmacogenomics, Chemotherapy-induced peripheral neuropathy, Personalized medicine... [Pg.301]


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See also in sourсe #XX -- [ Pg.9 , Pg.10 ]




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