PET imaging agents

F. Zeng, J.A. Southerland, R.J. Veil, J.R. Votaw, L. Williams, B.J. Ciliax, M.M. Goodman, Synthesis and evaluation of F-labeled FIMPYD as a PET imaging agent for beta-amyloid plaques, J. Label. Compds Radiopharm. 48 (2005) S41. 

Fiuorinated amine oxidase inhibitors as PET-imaging agents in the CNS 676... 

Other antibody-conjugated PET imaging agents include Cu-labeled monoclonal antibody 1A3, Y-labeled anti-Lewis Y monoclonal antibodies, Br-labeled human recombinant antibody fragment to the ED-B domain of fibro-nectin, and a review on isp 293-296 antigranulocyte... 

Anderson CJ, Dehdashti F, Cutler PD, Schwarz SW, Laforest R, Bass LA, Lewis JS, McCarthy DW. Cu-TETA-octreotide as a PET imaging agent for patients with neuroendocrine tumors. J Nucl Med 2001 42 213-221. 

Kung and coworkers have described preparation of F-labeled stilbenes as PET imaging agents for detecting /3-amyloid plaques in the brain. The authors used di-t-butyldichlorosilane to protect 2-hydroxypropyl-l,3-diol that was subsequently converted to the bromide 49. Alkylation of phenol 48 with the bromide 49 provided the ether 50 that was transformed into the desired F-labeled stilbene (eq 19). ... 

Synthesis, characterization and in vivo imaging in nonhuman primates of a series of carbon-11 reboxetine analogs as norepinephrine transporter (NET) PET imaging agents... 

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