Percutaneous implant experiment

In-Vivo Percutaneous Implant Experiment. The principle of percutaneous attachment has extensive application in many biomedical areas, including the attachment of dental and orthopedic prostheses directly to skeletal structures, external attachment for cardiac pacer leads, neuromuscular electrodes, energy transmission to artificial heart and for hemodialysis. Several attempts to solve the problem of fixation and stabilization of percutaneous implants(19) have been made. Failures were also attributed to the inability of the soft tissue interface to form an anatomic seal and a barrier to bacteria. In the current studies, the effect of pore size on soft tissue ingrowth and attachment to porous polyurethane (PU) surface and the effect of the flange to stem ratio and biomechanical compliance on the fixation and stabilization of the percutaneous devices have been investigated.(20)... 

Conclusions. Results from the biocompatibility studies in rabbit supratellar bursa, measurement of hydrophilic properties, lubrication and wear in-vitro studies, determination of viscoelastic properties, measurement of damping coefficient and impact test, total elbow joint replacement design and in-vivo percutaneous implant experiment, all indicate that this series of polyurethanes is an excellent candidate biomaterial for the prosthetic replacement of articular cartilage, artificial joint prostheses and percutaneous implantable devices. 

A Percutaneous Implant Experiment Using Porous Coatings for Soft Tissue Attachment A Preliminary Report, accepted for presentation at International Congress of Implantology and Biomaterials in Stomatology, June 9-12, 1980, in Kyoto, Japan. 

Cribier A, Eltchaninoff H, Tron C, et al. Early experience with percutaneous transcatheter implantation of heart valve prosthesis for the treatment of end-stage inoperable patients with calcific aortic stenosis. J Am Coll Cardiol 2004 43(4) 698-703. 

Chieffo A, Morici N, Maisano F, et al. Percutaneous treatment with drug-eluting stent implantation versus bypass surgery for unprotected left main stenosis a single-center experience. Circulation 2006 113 2542-7. 

Webb JG, Harnek J, Munt BI, et al. Percutaneous transvenous mitral annuloplasty initial human experience with device implantation in the coronary sinus. Circulation 2006 113 851-5. 

Dubreuil O, Basmadjian A, Ducharme A, et al. Percutaneous mitral valve annuloplasty for ischemic mitral regurgitation first in human experience with a temporary implant. Catheter Cardiovasc Interv 2007 69 1053-61. 

Marsolais, E.B. and Kobetic, R. (1986), Implantation techniques and experience with percutaneous intramuscular electrodes in the lower extremities, /. Rehabil. Res. De., 23. 

Multichannel percutaneous systems for gait restoration, with many channels, were suggested [60-62]. The main advantage of these systems is the plausibility to selectively activate many muscle groups. The implantable system also activates deep muscles that are not accessible by surface stimulation. A preprogrammed stimulation pattern that is a replica of the EMC pattern typical for humans with no motor disorders is delivered to muscles controlling the ankle, knee, and hip joints as well as to some trunk muscles. The experience of the Cleveland research team suggested that 48 channels are required... 

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