Peptococcus infection

Lincosamides (lincomycin and clindamycin) are representatives of a very small group of drugs synthesized up of an amino acid bound to an amino sugar. Lincosamides bind with the 50 S ribosomal subunit of bacteria and inhibit protein synthesis. They also inhibit pep-tidyltransferase action. Lincosamides are bacteriostatic antibiotics however, when they reach a certain level in the plasma, they also exhibit bactericidal action against some bacteria. Lincosamides are highly active against anaerobic infections such as Peptococcus, Peptostreptococcus, Actinomyces, Propionibacterium, and Clostridium fringens, a few types of Peptococcus and Clostridium. 

Intra-abdominal Infections - Enterococcus faecalis, S. aureus (penicillinase-producing), Staphylococcus epidermidis, E. coli, Klebsiella sp., Enterobacter sp., Proteus sp., M. morganii, P. aeruginosa, Citrobactersp., Clostridium sp., Bacteroides sp. including Bacteroides fragilis, Fusobacterium sp. Peptococcus sp., Peptostreptococcus sp., Eubacterium sp., Proplonibacterium sp.. Bifidobacterium sp. 

More severe infections - More severe infections, particularly those caused by Bacteroides fragilis, Peptococcus sp. or Clostridium sp. other than C. perfringens. 1.2 to 2.7 g/day in 2 to 4 equal doses. 

Skin and skin structure infections - Caused by Bacteroides sp. including the B. fragilis group, Clostridium sp., Peptococcus sp., Peptostreptococcus niger, and Fusobacterium sp. 

Gram-positive cocci. Leuconostoc, Micrococcus, Peptococcus, Staphylococcus (S. aureus, boils, infections), Streptococcus (S. pyogenes, scarlet fever, throat infections, S. pneumoniae, pneumonia)... 

Skin and skin structure infections caused by susceptible S. faecalis (enterococcus), E. coli, P. mirabilis, the indole-positive Proteus sp., P. vulgaris, and Providencia rettgeri, Klebsiella sp., Enterobacter sp.. Pseudomonas sp., Peptococcus sp., and Bacteroides sp. 

Clarithromycin (Biaxin) u Mycoplasma, Chlamydia, Mycobacterium. Most Gram pos Gram neg aerobes (including H.flu), Anaerobes Clostridium, B. melanino-genicus, Peptococcus. Mycoplasma or Pneumococcal pneumonia, Strep throat, upper respiratory infections caused by susceptible organisms. Staphylococcal skin infections. 

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