Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Peptide ligases

D.Y. Jackson, J. Burnier, C. Quan, M. Stanley, J. Tom, J.A. Wells, A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues. Science 266(5381) (1994) 243-247. [Pg.756]

Wang Z, Gu C, Colby T, Shindo T, Balamurugan R, Waldmann H, Kaiser M, van der Hoorn RAL (2008) p-Lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana. Nat Chem Biol 4 557-563... [Pg.83]

Peptide ligase Shorter-chain carboxylates, eventually acetate or formate Sugar kinases, etc. [Pg.10]

Inoue, M., Hiratake, J., and Sakata, K., Synthesis and characterization of intermediate and transition-state analogue inhibitors of y-glutamyl peptide ligases, Biosci. Biotechnol. Biochem., 63, 2248, 1999. [Pg.150]

Given the fact that the enzyme should not bind the substrate very strongly but must stabilize the transition state considerably, it is unlikely that a relatively simple enzyme can act as a universal peptide ligase. This premise was recently confirmed by reports by Hirsch-mann et al. [21] and by Jacobsen and Schultz... [Pg.170]

Enzymatic peptide synthesis, enzyme-catalyzed synthesis, the application of enzymes for peptide bond formation. The very complex ribosomal peptidyl transferase center is not suitable as a catalyst for simple practical peptide synthesis. However, enzymes which usually act as hydrolases, catalyzing the cleavage of peptide bonds, should be considered as peptide ligases due to the principle of microscopic reversibility. The protease-catalyzed peptide synthesis has been developed as a useful tool in the new catalytic synthetic approach based on protease-engineering and the develop-... [Pg.121]


See other pages where Peptide ligases is mentioned: [Pg.140]    [Pg.294]    [Pg.564]    [Pg.96]    [Pg.139]    [Pg.168]    [Pg.1709]    [Pg.642]    [Pg.649]    [Pg.67]    [Pg.67]    [Pg.835]    [Pg.167]    [Pg.167]    [Pg.169]    [Pg.171]    [Pg.121]    [Pg.109]    [Pg.346]    [Pg.315]    [Pg.318]    [Pg.342]    [Pg.412]    [Pg.420]    [Pg.420]   
See also in sourсe #XX -- [ Pg.167 ]




SEARCH



Ligase

Ligases

Peptide ligase

Peptide ligase

© 2024 chempedia.info