Pentobarbital Aminophylline

Incompatibilities Do not mix IV minocycline before or during administration with any solutions containing the following Adrenocorticotropic hormone (ACTH), aminophylline, amobarbital sodium, amphotericin B, bicarbonate infusion mixtures, calcium gluconate or chloride, carbenicillin, cephalothin sodium, cefazolin sodium, chloramphenicol succinate, colistin sulfate, heparin sodium, hydrocortisone sodium succinate, iodine sodium, methicillin sodium, novobiocin, penicillin, pentobarbital, phenytoin sodium, polymyxin, prochlorperazine, sodium ascorbate, sulfadiazine, sulfisoxazole, thiopental sodium, vitamin K (sodium bisulfate or sodium salt), whole blood. 

A single case report describes a man receiving intravenous aminophylline who had a 95% rise in the clearance of theophylline after he was given high-dose intravenous pentoharhital. In healthy subjects pentobarbital 100 mg daily for 10 days increased the clearance of oral theophylline by a mean of 40% and reduced the AUC by 26%, although there were marked intersubject differences. ... 

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