PdCl2, PPh

Ci2H25 C12H25O Br / Br S PdCl2 PPhs Cu(OAc)2 THF EtsN not measured 433 450 not measured not measured 56... 

CeHis XX CeHi3 PdCl2 PPhs Cu(OAc)2 PrzNH M = 9100 not measured not measured not measured not measured 89... 

Falck and co-workers [154] have studied reactions of alkoxyalkyltributyltins with acid chlorides, and in one case studied the stereochemistry of the reaction, which proceeded with 98% retention. Cyclopropyl transfer via reaction with a nucleoside bromide has also been carried out [155]. The traditional catalysts [Pd(PPh3)4 or PdCl2(PPh >)2] were used, but with various additives (LiCl, CuCN). 

Aryl chlorides typically do not react under these conditions. However, Miyaura has been able to extend the scope of this reaction to include aryl chlorides by changing the catalyst system to Pd(dba)2 and PCys and replacing pinacolborane with bis(pinacolato)diboron. Vinyl iodides and trifiates undergo borylation with pinacolborane under similar conditions in the presence of triphenylarsine (AsPEb) (eq 17). Benzylic halides react with pinacolborane in the presence of PdCl2, PPhs, and N,N-diisopropylethyl amine (eq 18). Borylation of allylic halides in the presence of Pt(dba)2, AsPhs, and EtsN leads to highly regio-and stereoselective allylboronates (eq 19). 

Zinc,copper dichlor obis (triphenylphosphine) palladium II) Zn,Cu PdCl2 PPh )2... 

Dichlorobis (triphenylphosphine)palladium (II) jcuprous iodide PdCl2 (PPh ) 2/Cul... 

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