PCI domain

Six of the CSN subunits contain PCI (proteasome, COP9 signalosome, initiation factor 3) domains and two contain MPN (Mpr-Padl-JV-terminal) domains [58]. These two characteristic domains have been found in three protein complexes the CSN, the 26S proteasome lid complex (lid) and the eIF3 complex. The two domains are composed of about 150 to 200 amino acids at the N- or C-terminus of the CSN subunits. Apparently, the PCI domain has been shown to be important for interactions between CSN subunits. Thus, it might have a scaffolding function [22, 59). 

MPN and PCI domains have been also found in subunits of the eIF3 complex. Because MPN and PCI domains are most likely involved in protein-protein interac-... 

Tsuge, T., Matsui, M., Wei, N. The subunit 1 of the COP9 signalosome suppresses gene expression through its N-terminal domain and incorporates into the complex through the PCI domain./. Mol. Biol. 2001, 305, 1-9. 

Hofmann, K., Bucher, P. The PCI domain a common theme in three multiprotein complexes. Trends Biochcm. Sci. 1998, 23, 204-205. 

Fig. 5.30 Scaling of lamellar domain spacing (reduced by N) with the degree of polymerization of the amorphous block, Nt, for various semicrystalline diblocks (Nojima et al. 1995). ( ) Data for PE-PEP diblocks from Rangarajan et al. (1993) (o) data for a PCI. PDMS PCL triblock from Lovinger et al. (1993) ( ) data for PCL-PB diblocks from Nojima et al. (1995).

Sequence motifs [33330 ANK (ANKyrin-like) repeats AAA (ATPases associated with a variety of cellular activities) domain or CAD (conserved ATPase domain) with Walker A and B motifs KEKE (motif rich in alternating lysine (K) and glutamate (E) residues) cys box of UBPs (ubiquitin-processing enzymes) nun- LRR (leucine-rich repeat)-like motif [ZD MPN (found in Mprland Padl in the N terminus) motif ISSSSSSS PCI (for proteasome, COP9andinitiation factor 3) motif H UCH (ubiquitin C-terminal hydrolases) block. 

As noted, solar cells fabricated with yrTCy BM active layers yielded devices with a long-standing record in PCE. Top-performing devices had an active layer that was a 3 2 7 PCy BM ratio cast from chloroform and were annealed at 110 °C. Chloroform is a relatively fast drying solvent and annealing was used to control domain size to lead from a PCE of 0.3% for as-cast devices to 4.4% for devices annealed at 110 °C. Similar PCEs could also be achieved for annealed 7 PCyiBM devices cast from other relatively low boiling point... 

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