Patent busting

Having said all this, a recent report from a major pharmaceutical company with one of the largest reported screening collections revealed that just over 50% of their current lead optimization efforts invoke a "fast follower" approach [114]. Why is this One might speculate that as most companies work on the same targets these days chemists find it easier to "patent bust" than wait for the results of an HTS campaign which may take months to develop. Possibly, when more novel targets are identified, HTS of enhanced collections will deliver upon the promise that they hold. 

From a chemical class (patent busting is an airform)... 

A new insecticide attracts much attention in terms of resistant management, environmental friendliness, and high activity. The research and innovation of insecticides characterized by a new mode of action is undoubtedly highly ranked in the area of agrochemical research, especially because it is much more challenging than research based on patent busting. 

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