Passive adhesion interactions

Figure 7.1 Schematic of three types of cell—material surface interactions (a) nonadsorption interactions (h) passive adhesion interactions (c) active adhesion interactions.

Material surface characteristics are important for cell—material surface interactions. Three types of cell—material surface interactions can be defined, as illustrated in Fig. 7.1, which is based on the concept proposed in Ref. 76. The first one is nonfouling interactions, in which case cells fail to interact with the material surface. This type of interaction is preferred for various biomedical applications such as artificial blood vessels and valves, artificial heart devices, catheters and blood preservation bags. The second type of interactions is passive adhesion, in which case interfacial response is controlled by physicochemical interactions between the material surface, adsorbed proteins and adhering cells. Surfaces in this category inhibit cellular metabolic changes. The adherent cells remain intact and are readily detached from these surfaces with little damage. The third is bioactive cell adhesion, in which cells activate... 

The purpose of this study is to evaluate the use of IR techniques to quantify molecular interactions in a model underfill resin. Such interactions should provide an insight into strengthening the adhesion between underfill resin and flip chip passivation coatings. 

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