Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Partition coeffident

Avdeef, A. pH-metric log P. 11 refinement of partition coeffidents and ionization constants of multiprotic substances. J. Pharm. Sci. 1993, 82, 183-190. [Pg.48]

I mmobili zed-artifidal-membrane chromatography measurements of membrane partition coeffident and predicting drug membrane permeability. /. Chromatogr. A. 1996, 728,113-128. [Pg.48]

Dias, N. C., Nawas, M. I., Poole, C. F. Evaluation of a reversed-phase column (Supelcosil LC-ABZ) under isocratic and gradient elution conditions for estimating octanol-water partition coeffidents. [Pg.352]

A., Tripodi, V. P., Sdoscia, S. L, Carducd, C. N. Relation between retention fadors of immunosuppressive drugs in microemulsion electrokinetic chromatography with biosurfactants and octanol-water partition coeffidents. [Pg.354]

Gluck, S. J., Benko, M. H., Hallberg, R. K., Steele, K. P. Indited determination of octanol-water partition coeffidents by microemulsion electrokinetic chromatography. J. Chromatogr. A 1996, 744,141-146. [Pg.354]

Berthod, A., Carda-Broch, S. Determination of liquid-liquid partition coeffidents by separation methods./. Chromatogr. A 2004, 1037, 3-14. [Pg.355]

Klopman, G., Zhu, H. Recent methodologies for the estimation of tt-odanol/water partition coeffidents and their use in the prediction of membrane transport properties of drugs. Minirev. Med. Chem. 2005, 5, 127-133. [Pg.377]

Meylan, W. M., Howard, P. H., Boethling, R. S. Improved method for estimating water solubility from octanol/ water partition coeffident. Environ. Toxicol. Chem. 1996, 75,100-105. [Pg.378]

Broto, P., Moreau, G., Vandycke, C. Molecular strucmres, perception, autocorrelation descriptor and SAR smdies system of atomic contributions for the calculation of the octanol-water partition coeffident. Eur. J. Med. Chem. 1984, 79, 71-78. [Pg.378]

Kraszni, M., Banyai, I., Noszal, B. Determination of conformer-spedfic partition coeffidents in odanol/water systems. J. Med. Chem. 2003, 46, 2241-2245. [Pg.405]

Waller, C. L. A three dimensional technique for the calculation of octanol-water partition coeffidents. Quant. Struct.-Act. Relat. 1994, 13,172-176. [Pg.405]

Niemi, G. J., Basak, S. C., Veith, G. D., Grunwald, G. D. Prediction of octanol water partition coeffident (fQ,w) using algorithmically-derived variables. Environ. Toxicol. Chem. 1992, 11, 893-900. [Pg.405]

I. V. Neural network modeling for estimation of partition coeffident based on atom-type electrotopological state indices. [Pg.405]

Huuskonen,. J., Villa, A. E., Tetko, I. V. Prediction of partition coeffident based on atom-type electrotopological state indices. f Pharm. Sci. 1999, 88, 229-233. [Pg.405]

Tetko, I. V., Tandiuk, V. Y., Villa, A. E. Prediction of n-octanol/water partition coeffidents from PHYSPROP database using artifidal neural networks and E-state indices./. Chem. Inf. Comput. Sci. 2001,... [Pg.405]

Rapid method for estimating the octanol-water partition coeffident (log P ) by microemulsion electrokinetic chromatography. ]. Chromatogr. B 2000, 745,117-126. [Pg.433]

Compound Partition coeffident octanol water IC30 (irM) ... [Pg.806]

Hitzel, L., Watt, A.P. and Locker, K.L. (2000) An increased throughput method for the determination of partition coeffidents. Pharmaceutical Research, 17, 1389-1395. [Pg.112]

Meyer and Overton dearly showed that fat-water partition coeffidents could be used... [Pg.93]

Pankow, J.F. 1998. Further discussion of the octanol-air partition coefficient, Koa, as a correlating parameter for gas/partide partitioning coeffidents. Atmos. Environ. 32 1493-1497. [Pg.280]

The range of the most convenient hydrophobidties of organic compounds for reversed-phase HPLC separation may be estimated approximately as 1 < log P < +5 (log P is the logarithm of the partition coeffident of the compound being characterized in the standard solvent system n-octanol-water). Highly hydrophilic substances with log P < 1 need the special... [Pg.497]

Clog P Logarithm of the calculated octanol/water partition coeffident (for... [Pg.185]

Reddy, KN. and Locke, M.A. (1996) Molecular properties as descriptors of octanol/water partition coeffidents of herhiddes. Water, Air and Soil Pollution, 86, 389—405. [Pg.1154]

This book discusses biological and geological cydes of various chemical substances and their potential exposure from cradle-to-grave. Contents indude physico-chemical properties, predicting degradation, partition coeffidents, kinetics of distribution phenomena, validating predictions, and hazard assessment. [Pg.71]

Two-element partition coeffidents have the advantage that they do not vary as extensively as single-element partition coeflndents with changes in melt composition. [Pg.106]

A bulk partition coefficient is a partition coeffident calculated for a rock for a specific element from the Nemst partition coeffidents of the constituent minerals and weighted according to their proportions. It is defined by the expression... [Pg.106]

In a rock containing SO % olivine, 30 % orthopyroxene and 20 % dinopyroxene, the bulk partition coeffident (D) for the trace element i would be... [Pg.106]

Measuring Partition coeffidents can be determined in natural systems from the analysis of partitidn minerals and their glassy matrix in rapidly cooled volcanic rocks. Provided suffident coefficients care is given to obtaining a clean mineral separate from unzoned minerals and a suffidently sensitive analytical technique is used, mineral/matrix or phenocryst/... [Pg.106]

Irving (1978) gives an excellent review of experimental determinations of partition >. coeffidents up imtil 1978 ... [Pg.107]

Pj is the volirme of the compartment i Q is the concentration of chemical in compartment i is the blood flow (arterial) to the compartment i C, is the concentration of chemical in the arterial blood and is the partition coeffidrart for the chemical between the tissue and the blood. The concentration difference between the arterial blood and the tissue concentration, as normalized by the partition coeffident, is the driver for the amoimt of chemical in the tissue. The sum of the... [Pg.92]

Table m. Comparison of E]q>erimental Liquid-Gas Partition Coeffidents of ... [Pg.16]

See other pages where Partition coeffident is mentioned: [Pg.377]    [Pg.378]    [Pg.40]    [Pg.477]    [Pg.567]    [Pg.25]    [Pg.106]    [Pg.150]    [Pg.157]    [Pg.308]   
See also in sourсe #XX -- [ Pg.259 , Pg.1062 ]



SEARCH



© 2024 chempedia.info