Paraquat reproductive effects

ACGIH TLV TWA Total Dust 0.5 mg/m Respirable Dust 0.1 mg/m (skin) Not Classifiable as a Human Carcinogen SAFETY PROFILE Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. A skin and eye irritant. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and Br . See also PARAQUAT. 

Resistance to paraquat among mammals varied substantially owing to inherent differences in sensitivity between species, to route of administration, and to reproductive state (Table 22.5). The lowest recorded doses of paraquat causing measurable adverse effects on growth, survival, or reproduction were (Table 22.5) ... 

Baud, F.J., P. Houze, C. Bismuth, J.M. Scherrmann, A. Jaeger, and C. Keyes. 1988. Toxicokinetics of paraquat through the heart-lung block. Six cases of acute human poisoning. Jour. Toxicol. Clin. Toxicol. 26 35-50. Bauer, C.A. 1983. The Effects of Paraquat on Various Reproductive and Growth Parameters in First and Second Generation Bobwhite Quail. Ph.D. thesis, Indiana State Univ., Terre Haute. 70 pp. 

Bauer, C.A. 1985. Effects of paraquat on reproduction and growth in northern bobwhite. Jour. Wildl. Manage. 49 1066-1073. 

Dial, C.A.B. and N.A. Dial. 1987a. Effects of paraquat on reproduction and mortality in two generation of mice. Arch. Environ. Contam. Toxicol. 16 759-764. 

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