Paragon System

Several publishers have opted to develop proprietary programs rather than purchase services from a third party. Examples include the American Chemical Society1 s ACS Paragon System and the American Institute of Physics Peer X-Press. These packages offer features and workflow similar to those contained in commercial editorial packages. 

Leading online submission packages Bench>Press, Editorial Manager, EJPress, Manuscript Central, and Rapid Review, as well as the ACS Paragon System and the American Institute of Physics Peer X-Press all use the author home page. This simple online profile contains the author s contact details and establishes a user name and password. The e-mail address entered here must be correct a typo could delay important e-mail notifications about acceptance or requests for revision. If the author has already established an account, future submissions can begin with the author login. 

Format ACS Paragon System Bench> Press Editorial Manager EJPress Manu- script Central Peer X-Press Rapid Review... 

Note The systems and their developers are as follows ACS Paragon System, American Chemical Society Bench>Press, HighWire Press Editorial Manager, Aries Systems EJPress, eJournal Press Manuscript Central, ScholarOne Peer X-Press, American Institute of Physics and Rapid Review, Cadmus Systems. 

CIVIL is accepted by the ACS Paragon System for submission of supporting information. 

Figure 20-10 Comparison of immunofixation electrophoresis (IFE) and immunoelectrophoresis (lEP) for two patients with monoclonal gammopathies. A, Patient specimen with an IgG (kappa, k) monoclonal protein as identified by IFE.The arrow indicates the position of monoclonal protein.After electrophoresis, each track except SPE is reacted with its respective antiserum, then all tracks are stained to visualize the respective protein bands. (SPE Chemically fixed serum protein electrophoresis IgG, IgA, IgM, k, and A, indicate antiserum used on each track.) B, Same specimen as in A, with proteins identified by lERThe arrow indicates the position of monoclonal protein. Norma control (C) and patient sera (S) are alternated. After electrophoresis, antiserum is added to each trough as indicated by the labels ig (polyvalent Ig antiserum), IgG, IgA, IgM, K, and A The antisera react with separated proteins in the specimens to form precipitates in the shape of arcs.The IgG and k arcs are shorter and thicker than those in the normal control, showing the presence of the IgG (k) monoclonal protein.The concentrations of IgA, IgM, and A,-iight chains are also reduced. C, Patient specimen with an IgA (lambda, A,) monoclonal protein identified by IFE procedure as described in A. D, Same specimen as in C with proteins identified by lEP as described in B.The abnormal IgA and A,-arcs for the patient specimen indicate an elevated concentration of a monoclonal IgA (A.) protein. Ait separations were performed using the Beckman-Coulter Paragon system.

System control and data acquisition are done with a personal computer using Paragon software. About 150 input and output modules were used for the two laboratory cells. This is expensive and may seem excessive, but a lot of the inputs and outputs are used for safety purposes so that the cell can operate unattended 24 hr a day, 7 days a week to get good long-term data. 

T0591 Paragon Environmental Systems, Inc., Paragon SVE/Oxidizers T0597 Pedco, Inc., Rotary Cascading Bed Incineration T0599 PerkinElmer, Inc., NoVOCs... 

Paragon has designed a system that combines soil vapor extraction (SVE) and oxidation tech-niqnes to remediate petrolenm-contaminated soils. The technology uses an SVE unit to volatihze petroleum hydrocarbons. The off-gases from this unit can then be treated using either a thermal or a catalytic oxidation method. The technology is no longer commercially available. 

Standardization of the AQS system enables paragon to provide sensors of superior value and quality, which enables car manufacturers to supply comfortable cars with a high performance air-quality management system. As for other components, the trend is that more and more compact cars are equipped with air-quality sensors to improve safety, health, and comfort. The customer is offered an effective air-quality management, with plenty more potential for the future. 

The density-matrix 0(N) TBMD scheme has recently been implemented successfully on Intel Paragon parallel computers by our group at Ames Laboratory, Iowa State University. Although optimization is still ongoing, extrapolation from current work indicates that practical simulations of 10,000-atom systems should be easily achievable on the 512-node... 

Bisschop J. and Entriken R. 1993. AIMMS The Modeling System. Paragon Decision Technology. 

Further examples of systems that provide advanced ATP functionality include Manugistics Supply Chain Planning and Optimization (SCPO) (see www.manu.com/ solutions/scm.asp), Paragon Applications Suite 4.0 (see www.adexa.com/getstarted.asp) and QAD s Supply Chain Optimizer (see www.qad.com/solutions/ mfgpro/). In all cases, the emphasis is on providing fast search for product availability across a global supply chain. 

Fig. 3 Electropherogram of Hb control A, S, and C. a, Results from CE with Beckman proprietary buffer running condition fused-silica capillary, 75 p,m (I.D.) X 27 cm detection at 415 nm Hb concentration is 2.5 g/L Hb A, 65.3% S, 23.9 and C, 10.8%. b, Results from the same sample by Acid-Hb gel with Paragon agarose gel electrophoresis system.

Any commercially available or homemade gel electrophoresis apparatus can be used for the elution-concentration system as long as the dimensions do not significantly vary. Electroblotting is carried out in a Bio-Rad Transblot cell or MiniTrans blot. For details on protein sequencing and HPLC peptide separation, reference is made to the article on amino-terminal protein sequence analysis by Heinz Nika and Ruedi Aebersold in this volume. The scalpels (No. 11) were from Paragon and the long needles (Cat. No. V2A 1415 LL-10) from Acufirm. The power supplies were from Pharmacia-LKB (EPS 500/400). 

The monomers flown on all three missions consisted of those that were completely miscible with one another as well as those which demonstrated extensive immiscibility. The miscible systems were assembled for their previously demonstrated permeability to atmospheric gases. This was in keeping with the original intent of the project and the objective of our commercial partner. Paragon Optical. In addition some of the monomeric mixtures were modified to contain metal atoms which would be incorporated into the polymer. The latter was an effort to enhance the permeability of the materials to specific gases and to determine the effect of low-gravity on the distribution of the atoms within the polymeric material. In STS-57, we observed that the immiscible... 

A Perkin Elmer Paragon 100 FT-IR spectrometer equipped with an MKII Golden Gate Single Reflection ATR system with a diamond ATR top plate was used to determine the changes in the chemical functionalities. The samples were clamped on the stage and scanned 4 times at 4 cm spectral resolution. The measurements were repeated at three locations and the collected spectra were averaged. 

Sony Image Analysis Systems, 3 Paragon Drive, Montvale, NJ 07645, USA 201)930 7098... 

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