Paced respiration

Exercise demonstrated an improvement in quality of life but did not improve vasomotor symptoms. Paced respiration, a form of deep, slow breathing, improved vasomotor symptoms in a small group of patients. 

Vignola AM, Chanez P, Chiappara G, Merendino A, Pace E, Rizzo A, et al Transforming growth factor-p expression in mucosal biopsies in asthma and chronic bronchitis. Am J Respir Crit Care Med 1997 156 591-599. 

A 23-year-old woman took chlorpropamide 5-10 g. She needed assisted respiration and cardiac pacing for bradycardia (probably due to blockade of potassium channels), fluid infusion, and forced diuresis for 3 days. Notwithstanding continuous glucose infusion and glucose boluses she relapsed into severe hypoglycemia with convulsions. Only on day 27 was her urine free of chlorpropamide and her blood glucose normal. 

DiMarco, A.F., Romaniuk, J.R., Kowalski, K.E., and Supinski, G.S. 1997. Efficacy of combined inspiratory intercostal and expiratory muscle pacing to maintain artificial ventilation. Am. J. Respir. Crit. Care Med. 156 122. 

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