P-Tolyl Acetate

SYNS ACETIC ACID-4-METHYLPHENYL ESTER p-ACETOXYTOLUENE 4-ACETOXYTOLUENE p-CRESOL ACETATE p-CRESYL ACETATE (FCQ FEMA No. 3073 4-METHYLBENZOIC ACID METHYL ESTER p-METHYLPHENYL ACETATE NARCEOL PARACRESYL ACETATE O p-TOLYL ACETATE p-TOLYL ETHANOATE... 

C9H5CIN203 3>chloro-4 nitroquinoline-1-oxide 14100-52-8 405.90 34.922 2 16003 C9H7F302 a,a,a-trifluoro-p-tolyl)acetic acid 32857-62-8 476.15 41.597 2... 

That the reaction is not an intramolecular rearrangement has been shown by the fact that a mixture of products is obtained when aluminum chloride is added to a solution of o-chloro-p-tolyl acetate and p-tolyl benzoate.66 Evidence for a common intermediate in this reaction and... 

The negative effect of sulfolane on the formation of o-HAP, already observed during the transformation of pure PA, could be explained by a competition between sulfolane and PA for adsorption on the acid sites. However, if this were the case, sulfolane would also decrease the initial rates of p-HAP and p-AXAP formations which involve adsorbed PA species (for the acylation of P or of PA). The initial rates of production of p-HAP and p-AXAP in sulfolane and in dodecane are less easy to compare than the rates of o-HAP production. Indeed the apparent greater production of p-HAP and p-AXAP in sulfolane could be due to the greater catalyst stability in this solvent. However, from the two experiments with H-BEA-10 (lOOmg and 500 mg) and from the experiment with H-BEA-70 it can be concluded that the initial production of p-HAP and p-AXAP is faster in sulfolane than in dodecane. Moreover, the same conclusion can be drawn from acylation of anisole with phenyl acetate or p-tolyl acetate the initial rate of formation of p-methoxyacetophenone is higher in sulfolane than in dodecane. Therefore sulfolane would have, besides a negative effect on the reaction rates due to its... 

The rate of anisole acylation depended on the acetate (Table 2). Initially it was about 1.5 times greater with p-tolyl acetate and with 2-methoxyphenyl acetate than with phenyl acetate, slightly lower with 2-methoxyhydroquinone diacetate, 2.5 times lower with the hydroquinone diacetate and very low with 2,4,6-trimethylphenyl acetate. The low reactivity of this latter acetate can be related to limitations in the rate of diffusion of this bulky compound in the BEA zeolite pores. Furthermore, a greater reactivity of this acetate was found with HFAU zeolites whose pore size is greater. Curiously, with hydroquinone diacetate (but not with the 2-methoxyhydroquinone acetate), there was a quasi immediate deactivation. We are carrying out additional experiments so as to understand how the reactivity of aromatic acetates changes with their nature and the zeolite acidity and porosity. 

With p-tolyl acetate, in which the position in para to the acetate group is blocked by the methyl group, no intermolecular reaction is observed and only 2-hydroxy-... 

Beilstein Handbook Reference) Acetic acid, 4-methylphenyl ester Acetic acid, p-tolyl ester 4-Aoetoxytoluene p-Acetoxytoluene AI3-01266 BRN 1908125 p-Cresol acetate p-Cresyl acetate Cresyl acetate Cresyl acetate, p- Cresylic xetate, P- EINECS 205-413-1 FEMA No. 3073 4-Methylbenzoic acid methyi ester 4-Methylphenyl acetate p-Methylphenyl acetate Narceol NSC 43244 Paracresyl acetate p-Tolyl acetate 4-Tolyl acetate p-Tolyl ethanoate. A synthetic perfume. Liquid bp = 212.5° d = 1.0512 Xm = 265, 271 nm (e = 446, 406, MeOH) slightly soluble in H2O, soluble in EtOH, EtzO, CCI4, CHCI3. 

Acetic acid, 4-methylphenyl ester p-tolyl acetate 172a, 174b, 1053, 3266, 3370 ... 

Synonyms Acetic acid-4-methylphenyl ester 4-Acetoxytoluene p-Acetoxytoluene Acetyl p-cresol p-Cresol acetate p-Cresylic acetate 4-Methylbenzoic acid methyl ester 4-Methyl phenyl acetate p-Methylphenyl acetate Paracresyl acetate p-Tolyl acetate p-Tolyl ethanoate Classification Aromatic ester Empirical C9H10O2 Formula CH3CO2C6H4CH3 Properties Colorless liq., anise sweet fragrant odor sol. in fixed oils, propylene glycol misc. with alcohol, ether insol. in water, glycerin m.w. 150.18 dens. 1.047 b.p. 210-211 C dec. 360 C flash pt. 90 C ref. index 1.5010 Toxicology LD50 (oral, rat) 1900 mg/kg, (skin, rabbit) 2100 mg/kg mod. toxic by ing. and skin contact irritant TSCA listed Precaution Combustible Hazardous Decomp. Prods. Heated to decomp.. 

Acetyl 5>bromo-.2-nitro-p>tolyl acetate. Plates. M.p. 121°,... 

Acem p-tolyl acetate. Narceol. B.p. 212-13°. Sol. EtOH, EtgO, CHClj. Spar. sol. HjO. Volatile in steam, 1 4991. 

Also obtained by UV light irradiation of p-tolyl acetate at 25°,... 

Also obtained by UV light irradiation on p-tolyl acetate in methanol at 25° (26%) [2315]. (There is a 1,2-migration of the methyl group). 

---