P-d-mannuronic acid

Pneumococcus, polysaccharides from, 6-7 Poly(a-L-guluronic acid), 353, 355-356,415 Poly(P-D-mannuronic acid), 353-354,414 Polysaccharides, 311 -439 amino sugar derivatives, 166 chemical repeating units, 321, 324-325... 

Algin (alginic acid) is composed of a-L-GulpA and P-d-ManpA (P-D-mannuronic acid) linked by 1—>4. 

Alginate is a family of linear anionic polysaccharides, which can be considered as copolymers of (1 4) linked a-l-glucuronic acid (G) and p-d-mannuronic acid (M)... 

FIGURE 31.5 Chemical structure of alginate showing the a-L-guluronic and P-D-mannuronic acids blocks. 

Definition Hydrophilic colloidal carbohydrate derived from brown seaweed, Phaeophyceae polysaccharide composed of p-d-mannuronic acid residues... 

Alginates are polysaccharides wih gel-forming properties composed of 1,4-linked P-D-mannuronic acid, a-L-guluronic acid and alternating P-D-mannuronic acid-a-L-guluronic acid blocks. Alginates stimulated human monocytes to produce high levels of tumour necrosis factor-a, interleukin-6 and interleukin-1 (Otterlei et al. 1991). 

Common name - alginic acid poly(1,4-a,L-guluronic-co-1,4-p-D-mannuronic acid) ... 

Monomer(s) structure - p-D-mannuronic acid and a-L-guluronic acid ... 

FIGURE 9 Structure of alginate a-L-guluronic acid (G) P-D-mannuronic acid (M), MG block copolymer. 

The poly(saccharide) is a linear co-polymer of p-D-mannuronic acid and a a-L-guluronic acid linked by (l->4) bonds to give blocks of poly-(mannuronic acid) (M-blocks), blocks of poly(guluronic acid) (G-blocks), and blocks in which the two acidic monosaccharides occur in mixed sequences (MG-blocks). ... 

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