Oxypropionic acids

The effect of the mobile phase modifier was investigated for a series of phen-oxypropionic acid (PEA) herbicides on a teicoplanin CSP [85, 86] an increasing enantioselectivity was found with increasing MeOH content in the mobile phase, attributed to restriction of the solute association with the TE CSP, which led to favorable stereoselective interactions. 

Andre, C. and Guillaume, Y.C., Reanalysis of chiral discrimination of phen-oxypropionic acid herbicides on a teicoplanin phase using a bi-Langmuir approach, Chromatographia, 58, 201,2003. 

Ammonium pyruvate, which is first formed, is tautomeric with a-amino-oxypropionic acid, into which it changes —... 

Cramer, the discoverer, showed that, when serine was treated with nitrous acid, it was converted into glyceric acid, and he recognised it as an aminolactic acid. It was regarded as a-amino-jS-oxypropionic acid, but this was only definitely proved when it was synthesised by Fischer and Leuchs in 1902 from glycollic aldehyde, hydrogen C anide and ammonia, which is the first instance of the employment of Strecker s method to build up oxyamino acids from oxyaldehydes. 

Hydracrylic Acid (Ethylenelactic Acid=/3-oxypropionic Acid). —Resin and a little formic acid were found present in the electrolyte surrounding the positive pole. 

The fragmentation pathways for the methyl esters are strongly dependent on the type of acid, i.e. whether a derivative of phenoxyacetic acid, phen-oxypropionic acid, or phenoxybutyric acid, and on the nature of the substitution of the aromatic ring. The methyl esters of chlorinated phenoxyacetic and phenoxypropionic acids show reasonably abundant molecular ions (about 20% relative to the base peak) which, together with the chlorine isotope patterns, permit easy identification of these compounds. In contrast, the spectra of the methyl esters of chlorinated phenoxybutyric acids are dominated by the fragment ion at m/z 101, with only low abundance of molecular ions. However, the spectra also show... 

Stereoselective dehalogenation of 2-haloaIkanoic acids has been demonstrated for a number of halidohydrolases (80-82). Figure 77 details the production of an L-haloacid intermediate used in the production of phen-oxypropionic acid herbicides. The R enantiomer of chloropropionic acid is selectively hydrolyzed to (S)-lactic acid due to an inversion of configuration that occurs during the hydrolysis (83). (S)-2-chloroproprionic acid is used as a chiral synthon to produce a number of (R)-phenoxypropionic acid herbicides, for example, Fusilade 2000 (ICI). 

Chuiko, Tertykh, and co-workers (88, 200-203, 265-269, 291) studied chemical reactions on the silica surface. As a result, practical applications were found (88, 291) for methylaerosils butoxyaerosils aerosils modified with monoethanolamine, ethylene glycol, and a-oxypropionic acid and other highly dispersed organosilicas. To classify reactions on the silica surfaces, use was made of the electrophilic and nucleophilic mechanisms developed by Ingold (292). 

A more circuitous route to 121 utilizes L-alanine (122) as the chiral source [47] (Scheme 18). In the first step, nitrous acid deamination of 122 in acetic acid produces ( S)-( — )-acet-oxypropionic acid (123) with greater than 96% retention of configuration [48]. The acid 121 is obtained in 55% overall yield from 123. 

In conjunction with Gumlich, Curtius has investigated the linking of hippurazide with /9-amino-a-oxypropionic acid and with j8-amino-butyric acid. With the former compound, the combination took place with the hydroxyl group instead of with the amino group, hippuryl-a-oxy-yS-aminopropionic acid,... 

Bilirubin, chlorophen-oxypropionic acid, chrysin, clofibrate... 

Adhesives, coatings, and moldings 2-Allyloxyacetic acid, 3-allyl-oxypropionic acid, and 4-allyl-oxybutyric acid United States 2,602,786 1952 Swift Co. 

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Horwitz JP (2005) Synthetic modification of the 2-oxypropionic acid moiety in 2- 4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy (propionic acid (XK469), and consequent antitumor effects. Part 4. Bioorg Med Chem 13(12) 3910-3920. doi 10.1016/j.bmc.2005.04.011... 

The addition of alcohols to form the 3-alkoxypropionates is readily carried out with strongly basic catalyst (25). If the alcohol groups are different, ester interchange gives a mixture of products. Anionic polymerization to oligomeric acrylate esters can be obtained with appropriate control of reaction conditions. The 3-aIkoxypropionates can be cleaved in the presence of acid catalysts to generate acrylates (26). Development of transition-metal catalysts for carbonylation of olefins provides routes to both 3-aIkoxypropionates and 3-acryl-oxypropionates (27,28). Hence these are potential intermediates to acrylates from ethylene and carbon monoxide. 

SYNS ATROPIN (GERMAN) EYEULES dl-HYOSCYAMINE 2-PHENYLHYDRACRYLIC ACID-3-a-TROPANYL ESTER P-PHENYL-y-OXYPROPION-SAEURE-TROPYL-ESTER (GERNLAN) l-0-H,5-a-H-TROPAN-3-a-OL ( )-TROPATE (ESTER) dl-TROPAN-YL-2-HYDROXY-1-PHENYLPROPIONATE TROPIC ACID, ESTER with TROPINE TROPIC ACID-3-a-TROPANYL ESTER TROPINE TROPATE dl-TROPYLTROPATE ( )-TROPYL TROPATE... 

Actylol Acytol ethyl a-hydroxypropionate ethyl-2-hydroxy-propanoate ethyl-2-hydroxypropionate ethyl-S-(-)-2-hydr-oxypropionate 2-hydroxypropanoic acid ethyl ester lactic acid ethyl ester propanoic acid 2-hydroxy-ethyl ester Purasolv EL Solactol. 

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