Oxygen radicals systems

Winterbourn, C.C. (1990). Neutrophil oxidants production and reactions. In Oxygen Radicals Systemic Events and Disease Process (eds. D.K. Das and W.B. Essman) pp. 31-70. Karger, Basel. 

Modulation of electrogenic Na/Ca exchange current by oxygen radical generating systems in isolated guinea pig ventricular myocytes. J. Mol. Cell. Cardiol. 24 (Suppl V), S28. 

Braughler, J.M, and Hall, E.D. (1989). Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Rad. Biol. Med. 6, 289-301. 

Nonaka, A., Manabe, T., Kyt ku, T., Tamura, K. and Tobe, T. (1990). Changes in lipid peroxide and oxygen radical scavengers in caerulein-induced acute pancreatitis. Imbalance between the offensive and defense systems. Digestion 47, 130-137. 

Carmichael, P.L., She, M.N. and Phillips, D.H. (1992). Detection and characterization by P-postlabelling of DNA adducts induced by a Fenton-type oxygen radical-generating system. Carcinogenesis 13, 1127-1135. 

Volume 105. Oxygen Radicals in Biological Systems Edited by Lester Packer... 

Xanthine oxidase, a widely used source of superoxide, has been frequently applied for the study of the effects of superoxide on DNA oxidation. Rozenberg-Arska et al. [30] have shown that xanthine oxidase plus excess iron induced chromosomal and plasmid DNA injury, which was supposedly mediated by hydroxyl radicals. Ito et al. [31] compared the inactivation of Bacillus subtilis transforming DNA by potassium superoxide and the xanthine xanthine oxidase system. It was found that xanthine oxidase but not K02 was a source of free radical mediated DNA inactivation apparently due to the conversion of superoxide to hydroxyl radicals in the presence of iron ions. Deno and Fridovich [32] also supposed that the single strand scission formation after exposure of DNA plasmid to xanthine oxidase was mediated by hydroxyl radical formation. Oxygen radicals produced by xanthine oxidase induced DNA strand breakage in promotable and nonpromotable JB6 mouse epidermal cells [33]. 

Quercetin and rutin suppressed photosensitized hemolysis of human erythrocytes with ho values equal to 40 p.mol l-1 and 150 jjlmt>I I 1, respectively [139]. Suppression of photohemolysis was accompanied by inhibition of lipid peroxidation. Morin inhibited oxygen radical-mediated damage induced by superoxide or peroxyl radicals to the human cells in the cardiovascular system, erythrocytes, ventricular myocytes, and saphenous vein endothelial cells [140]. Rutin protected against hemoglobin oxidation inside erythrocytes stimulated by prooxidant primaquine [141],... 

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