Phenylalanine, oxidized starch

The addition of phenylalanine to the previously described starch base materials (Control and Oxidized starches) was done on a lOX (w/w) level for covalent attachment. The Oxidized starch was apparently more conductive to cyanogen bromide activation for amino acid attachment than was the Control starch (92X attachment versus 67X, respectively). The addition of aspartame was also completed for the Oxidized (ii) starch polymer on a level of... 

Substantial improvement (about 50%) of lemon oil encapsulation efficiency was attained for the covalently-linked phenylalanine-Oxidized starch wall material over the Oxidized starch control. In fact, this particular glycoamine resulted in lemon oil retentions following drying in the mini-spray dryer which surpassed both the Control and lipophilic starches (See Table IV). Dry blending phenylalanine with the Oxidized starch base exhibited the benefits associated with covalently linked glycoamine production via lemon oil vapor phase flux analysis. 

The other two glycoamine derivatives failed to substantially improve polymer performance. Aspartame linkage to the Oxidized starch resulted in improved lemon oil encapsulation efficiency over the Oxidized material, alone, but not to the extent of the phenylalanine glycoamine polymer. Covalent attachment of phenylalanine to the Control starch was actually a slight detriment to lemon oil retention versus the control starch (48.7% retention in the mini-dryer versus 50.4%, respectively), although this difference was not deemed significant. 

Of the myriad of modified starch systems tested, ranging from simple enzymically dextrinized starches to covalently attached amino acids and peptides onto dextrinized and/or oxidized (hypochlorite or periodate) corn starch bases, two polymers were selected as holding promise. The first system was a low dextrose equivalent (DE 5.7) enzyme-modified corn starch. The second starch-based polymer developed was a periodate-oxidized, amylase-dextrinized, covalently-attached phenylalanine glycoamine. 

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See also in sourсe #XX -- [ , ]

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