Iodine oxidation with

Analytical and Test Methods. Analysis and test methods are similar to those for sodium thiosulfate. Sulfite is determined by an indirect method based on the titration of the acid Hberated when both the sulfite and thiosulfate are oxidized with iodine solution (69). 

CHCI3), and closely resembles corybulbine. It contains three methoxyl groups, and on oxidation with iodine yields dehydroisocorybulbine the hydriodide of the latter is reduced by zinc and sulphuric acid to dl-isocory-bulbine, m.p. 165-7°. 

Catalytic dehydrogenation using palladium/maleic acid has been used to convert tetrahydro-j8-earbolines of general structure 142 into the dihydro-jS Carbolinium salts (143) A similar transformation has been carried out by oxidation with iodine. ... 

Nakajima and Okawa prepared cysteine (250 Scheme 3.92) by treating aziridine 127a with dry H2S gas in the presence of a catalytic amount of BF3 Et20 [141]. The resulting thiol 248 was then oxidized with iodine to afford disulfide 249 in 70% overall yield. Removal of the Cbz protecting group afforded cysteine (250). 

Reaction of the tetrazolide of phosphorous acid diester with a S -protected thymidine and subsequent oxidation with iodine yields the corresponding thymidine phosphortriester [961... 

The isolation of calycanthine (9) in 1888 by Eccles [28] and the subsequent proposition for its origins in the oxidative dimerization of tryptamine by Woodward [29] and Robinson [30] had prompted several key synthetic studies based on a biomimetic approach. Hendrickson was the first to experimentally verify the plausibility of forming the C3-C3 linked dimers through an oxidative radical dimerization strategy (Scheme 9.2a). He demonstrated that the sodium enolate of a tryptamine-derived oxindole could be oxidized with iodine to afford a mixture of three possible stereoisomers. The racemic product was isolated in 13 % yield, while the meso product was isolated in 8 % yield. Global reduction of the oxindole and carbamates afforded the first synthetic samples of chimonanthine (7) [9a],... 

The final method for constructing epidithiodiketopiperazine motifs relied on the nucleophilic thiolation of /V-acyliminium ions. Access to alpha-oxidized diketopi-perazine structures was central to this approach, and key developments were made in this regard. Schmidt first demonstrated the feasibility of this ionization approach in 1973 by conversion of proline anhydride to its diacetate using Pb(OAc)4 [42], Hydrolysis of the acetates, ionization of the hemiaminals with zinc chloride in the presence of hydrogen sulfide, and oxidation with iodine provided the epidisulfide of interest. In 1975, Matsunari reported access to alpha-methoxy diketopiperazines,... 

The dinuclear [Fe(C5H5)(C0)2(CgH4S8-C8H4Sg)Fe(C5H5)C02] organometallic complex exhibits ligand-centered oxidation at a low potential [94]. The crystalline material that forms upon chemical oxidation with iodine contains both I3 and I5 anions and has a room temperature compressed pellet conductivity of 1.7 x 1CT4 S cm-1. 

A set of Pacific open-ocean samples were analysed for iodate-iodine using both the procedure which incorporates pre-oxidation with iodine water and that which does not. Also, in a similar exercise total iodine was determined using both the method that incorporates pre-oxidation with bromine water and the catalytic method using the reaction between Ce(IV) and As(III) [81]. Variance tests showed that differences between either replicates or methods was not significant. 

Although the reaction of a titanium carbene complex with an olefin generally affords the olefin metathesis product, in certain cases the intermediate titanacyclobutane may decompose through reductive elimination to give a cyclopropane. A small amount of the cyclopropane derivative is produced by the reaction of titanocene-methylidene with isobutene or ethene in the presence of triethylamine or THF [8], In order to accelerate the reductive elimination from titanacyclobutane to form the cyclopropane, oxidation with iodine is required (Scheme 14.21) [36], The stereochemistry obtained indicates that this reaction proceeds through the formation of y-iodoalkyltitanium species 46 and 47. A subsequent intramolecular SN2 reaction produces the cyclopropane. 

Hydroiodic acid (HI) possesses strong reducing characteristics which renders the oxidation with iodine into a reversible reaction as follows ... 

Oxidation with iodine resulted in an octamethylferricinium-based anion-exchanger that was successfully used to separate oligonucleotides (dJu-dTis). 

Native urine should be protected from light and stored at -20°C until processed. Oxidized urine sample can be stored at room temperature, but light protection is still recommended. Two procedures for the oxidation of urine (and other samples) are used (1) oxidation with manganese dioxide (Mn02) under acidic conditions, and (2) oxidation with iodine (iodine/potassium iodide, I2/KI) under acidic and basic conditions. The Mn02 oxidation method is a routine method used to quantify total pterins (fully oxidized neopterin, monapterin, biopterin, primapterin, isoxanthopterin, and pterin) the I2/KI method is used according to Fukushima and Nixon [11] for the differential oxidation of pterins and quantification of BH4. Total biopterin represents the sum of BH4, BH2, and fully oxidized biopterin. Under acidic conditions BH4 and BH2 are oxidized to biopterin, while under basic conditions only BH2 is oxidized to... 

The macrocyclic phthalocyanine ligand will form a complex Pt(phthalocyanine).1106 The crystal structure shows two polymorphs present because of molecular packing.1107 The platinum is in a square planar coordination geometry with a mean Pt—N distance of 1.98 A. The complex can be partially oxidized with iodine to give conducting mixed valence solids.1108 Eighteen fundamental and overtone combination bands are observed in the resonance Raman spectrum of platinum phthalocyanine, and from this data the symmetry of the excited singlets are found to be Dy.. Qlv or D2.1109... 

Oligoribonucleotides are more difficult to handle than oligodeoxyribonucleotides, mainly because of their sensitivity towards nucleases. For the synthesis of oligoribonucleotides on insoluble supports, protection of the 2 -hydroxyl group is required, which must be stable towards oxidation with iodine and the acidic conditions of DMT depro-... 

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