Oxford Gene Technologies

Oxford Gene Technologies offers services and licenses their proprietary technologies. The array technique surveys hybridization across gene sequences. The customized DNA microarray service supports research activities, and includes consultation, experimental design, data analysis, and interpretation. 

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While Affymetrix s early entry into the DNA microarray market afforded it a formidable position, the company has competitors. In order to commercialize the in situ array, it became clear that access to certain intellectual properties, especially the Southern patent (Oxford Gene Technologies or OGT), was required. Affymetrix obtained a license through a business relationship with Beckman Coulter which originally held the first and exclusive Southern license and later relinquished its exclusivity. Beckman Coulter and Affymetrix entered into a joint venture with Array Automation LLC to automate the processing of Affymetrix chips. Now that license to the Southern technology is available from OGT, others are permitted to commercialize in situ microarrays by alternative chemical S5mthesis approaches. 

Yang, N.S. and Christou, P. (1994) Particle Bombardment Technology for Gene Transfer. Oxford University Press, New York. 

Yang, N.-S. and Ziegelhoffer, P. (1994) The particle bombardment system for mammalian gene transfer. In N.-S. Yang and P. Christou (eds) Particle Bombardment Technology for Gene Transfer. Oxford University Press, New York, pp. 117-141. 

Malcom, J. W. Malone, J. H. In Fundamentals of Advanced Omics Technologies From Genes to Metabolites Simo, C. Cifuentes, A. Garcfa-Canas, V., Eds. Elsevier Oxford, UK, 2014 pp 325-354. 

Maureen D. McKelvey Evolutionary Innovations The Business of Biotechnology (New York Oxford University Press, 1996), chs. 6-8, has a detailed, well-documented, and fascinating account of the formation of Genentech and its commercialization of the new rDNA technology. For the Lilly and Kabi contracts, see ibid., pp. 134-135, 142, for other contracts, p. 137, for Protopin, pp. 249-252. See also Teitelman, Gene Dreams, pp. 11-14, 24-26, 193-194. 

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