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Oxatomide

Chemical Name 1-[3-[4-(Dlphenvlmethyl)-1-piperazlnyl] propyl] -2-benzimidazolone Common Name Oxatimide Structural Formula /  [Pg.1128]

Chemical Abstracts Registry No. 60607-34-3 Trade Name Manufacturer [Pg.1128]

Alkylation of the monobenzhydryl derivative of piperazine ( ) with the same alkylating agent gives oxatomide (59), after removal of the protecting group.This agent shows antihistaminic activity as well as some mediator release inhibiting activity, a... [Pg.173]

Tindurin - Pyrimethamine Tinidil Isosorbide dinitrate Tinigyn - Tinidazole Tinol - Dipyridamole Tinset - Oxatomide Tintorane Warfarin sodium Tinver - Salicylic acid... [Pg.1748]

Oxatomide (l- 3- [4-(diphenylmethyl)-l-piperazinyl] propyl)-l,3-dihydro-2H-benzimidazol-2-one) is an antiallergy drug. Akamatsu has reported that oxatomide decreases neutrophil-generated superoxide anion and hydrogen peroxide formation in a dose-dependent manner. The authors hypothesize that the drug is inhibiting NADPH-dependent oxygen metabolism within the neutrophil (Akamatsu et al., 1993). [Pg.273]

Akamatsu, H., Miyachi, Y., Asada, Y. and Niew, Y. (1993). The effect of oxatomide on neutrophil oxygen radical generation. Biol. Pharm. Bull. 16, 568-570. [Pg.274]

Inhibitors of histamine release One of the effects of the so-called mast cell stabilizers cromoglycate (cromolyn) and nedocromil is to decrease the release of histamine from mast cells (p. 72, 326). Both agents are applied topically. Release of mast cell mediators can also be inhibited by some Hi antihistamines, e.g., oxatomide and ketotifen, which are used systemically. [Pg.116]

C3H()BrCI 109-70-6) see Acetophenazine Carfenazine Cisapride Cloeaprainine Desipramine Dilazcp Etoperidone Gallopamil Metopimazine Opipramol Oxatomide Perphenazine Pipamazine Piperacetazine Reproterol Tirofiban hydrochloride Verapamil Vincamine (I ,3p,7a)-7-bromocholest-5-cnc-I,3,25-triol triacetate (C4,H5 Br06) sec Calcitriol... [Pg.2312]

XATHI0LANE-2,2-DIOXIDE see Pi IL400 OXATIMIDE see OMGOOO OXATOMIDA see OMGOOO OXATOMIDE see OMGOOO 5-OXATRICYCLO(8.2.0.0. )DODECANE, 4,12,12-TRIMETHYL-9-METHYLENE-, (1R,4R,6R,10S)- see CCNIOO... [Pg.1822]

De Parades V, Roulot D, NeyroUes N, Rautureau J, Coste T. Hepatite cytolotique an cours de 1 administration d oxatomide. [Acute cytolytic hepatitis during administration of oxatomide.] Gastroenterol Clin Biol 1994 18(3) 294. [Pg.315]

See other pages where Oxatomide is mentioned: [Pg.710]    [Pg.137]    [Pg.137]    [Pg.254]    [Pg.273]    [Pg.243]    [Pg.1128]    [Pg.1624]    [Pg.1631]    [Pg.1700]    [Pg.1512]    [Pg.2301]    [Pg.2301]    [Pg.2335]    [Pg.273]    [Pg.345]    [Pg.366]    [Pg.1303]    [Pg.1591]    [Pg.710]    [Pg.2545]    [Pg.2545]    [Pg.238]    [Pg.1512]    [Pg.2301]    [Pg.408]    [Pg.545]    [Pg.263]    [Pg.1057]    [Pg.307]   
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