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Oxaliplatin alkylating agent

Oxaliplatin - alkylating agent causes DNA cross-linking... [Pg.177]

Other subgroups of alkylating agents are the nitrosoureas (examples carmustine, BCNU lomustine, CCNXJ) and the triazenes (example dacarbazine, DTIC). Platinum derivatives (cisplatin, carboplatin, oxaliplatin) have an action that is analogous to that of alkylating agents (formation of crosslinks) and therefore are appended to this class, as well. [Pg.154]

Heavy metal compounds used to treat cancer include cisplatin, carboplatin, and oxaliplatin (see Table 36-6). These drugs, which contain platinum, are also known as platinum coordination complexes.10,27 Heavy metal drugs act like the alkylating agents that is, they form strong cross-links between and within DNA strands,... [Pg.579]

See other pages where Oxaliplatin alkylating agent is mentioned: [Pg.243]    [Pg.1169]    [Pg.606]    [Pg.2308]    [Pg.867]    [Pg.62]   
See also in sourсe #XX -- [ Pg.5 , Pg.5 , Pg.5 , Pg.54 , Pg.59 , Pg.61 ]



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