Overpressure setting

Crude plasma quickly fouls the protein separation column with lipids, usually after only three injections. These lipids can be removed by washing the column with water, then with 20% DMSO/MeOH, and finally with water again before returning to buffer. DMSO/MeOH is fairly viscous and you may have to drop the flow rate to avoid triggering your overpressure setting. 

Treatment Reset overpressure setting to a higher value, if the column can tolerate it. 

Pressure of the reactor coolant system (including cold overpressure settings) ... 

An intermediate casing is usually set above the reservoir in order to protect the water bearing, hydrostatically pressured zones from influx of possibly overpressured hydrocarbons and to guarantee the integrity of the well bore above the objective zone. In mature fields where production has been ongoing for many years, the reservoir may show depletion pressures considerably lower than the hydrostatically pressured zones above. Casing and cementing operations are covered in section 3.6. 

Pressure-relief-device requirements are defined in Subsec. A. Set point and maximum pressure during relief are defined according to the service, the cause of overpressure, and the number of relief devices. Safety, safety relief, relief valves, rupture disk, breaking pin, and rules on tolerances for the reheving point are given. 

Set the release pressure of a rupture disk or other vent closure as close to the operating pressure as practical. Note that the maximum overpressure in a vented explosion will exceed the opening pressure of the vent closure. 

Plants, situations, and causes of overpressure tend to be dissimilar enough to discourage preparation of generalized calculation procedures for the rate of discharge. In lieu of a set procedure most of these problems can be solved satisfactorily by conservative simplification and analysis. It should be noted also that, by general assumption, two unrelated emergency conditions will not occur simultaneously. 

The quantity of material to be relieved should be determined at conditions corresponding to the PR valve set pressure plus overpressure, not at normal operating conditions. Frequently, there is an appreciable reduction in required PR valve capacity when this difference in conditions is considerable. The effect of friction pressure drop in the connecting line between the source of overpressure and the system being protected should also be considered in determining the capacity requirement. If the valve passes a liquid which flashes or the heat content causes vaporization of liquid, this should be considered in determining PR valve size. 

Steam Turbine - A PR valve is required on the steam inlet to any steam turbine if the maximum steam supply pressure is greater than the design pressure of the casing inlet. The PR valve should be set at the casing inlet design pressure and sized such that overpressure of the casing is prevented, under conditions of wide open steam supply and normal exhaust flow. 

Once the set pressure is reached, the valve opens fully and remains open, so long as the set point is exceeded. There is no need for overpressure or minimum flow to keep it open. Thus, it is not subject to chattering at low discharge rates. 

Conventional PR valves and discharge systems should be designed such that built-up back pressure does not exceed 10% of set pressure (both measured in psig), to avoid chattering problems. In the case where a pressure relief valve system is sized for fire conditions, with 21 % overpressure, built-up back pressure up to 21 % of set pressure is permissible. However, the lower rates resulting from other contingencies still must meet the 10% limitation. 

APg = allowable venting overpressure (psi), that is, the maximum venting pressure minus the relief device set pressure Pp = maximum venting pressure (psig)... 

An 800-gal reaetor eontaining a styrene mixture with a speeifie heat of 0.6 eal/gm °C has a 10-in. rupture disk and a vent line with equivalent length = 400. The vessel MAWP is 100 psig and the rupture disk set pressure is 20 psig. The styrene mixture had a self-heat rate of 60°C/min at 170°C as it is tempered in a DIERS venting test. Determine the allowable reaetor mixture eharge to limit the overpressure to 10% over the set pressure. 

Overpressure A pressure increase over the set pressure of the relief device, usually expressed as a percentage of gauge set pressure. 

Pi = flowing pressure, psia (set pressure + overpressure + 14.7) Overpressure is normally 10% of set pressure. MW = molecular weight of gas Z = compressibility factor... 

AP = set pressure plus allowable overpressure minus back pressure, psig... 

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