Overlap of inputs cortico-cortical organization

This latter conclusion has important implications in the context of the functional organization of the striatum, and in particular with the concept of parallel functional cortical-basal ganglia circuits as put forth by Alexander and his colleagues (Alexander and Crutcher 1990 Alexander et al. 1986, 1990). The basis of the matrisome concept is that the mulitple innervation zones provided from a single cortical site, represent functional units in which cortical information is reorganized. Such discontinuous patterns of corticostriatal inputs are clearly established from a number of studies employing a variety of tracers in a number of species over an extended period of time. However, the basis of such patterns is still open to study. 

Cellular heterogeneity of the corticostriatal projection could also help to explain the absence of a single simple rule governing the convergence of corticostriatal inputs. Rules based on cortico-cortical connections, like that suggested by Yeterian and van Hoesen 

STRIATAL OUTPUT SYSTEMS TOPOGRAPHY / CONVERGENCE / DIVERGENCE 

The topographic organization of cortical inputs to the striatum, of striatal outputs to the globus pallidus (external segment), internal segment of the globus pallidus (en- 

There are two other distinctive features of striatal output organization. The first is the segregation of the projections of the patch-matrix compartments of the striatum. This will be discussed in a later section. The second, which has been mentioned, is the dual projection zones of striatal inputs in both the globus pallidus and substantia nigra. As will be described these dual projection systems appear also in the organization of other components of the basal ganglia, including the projection of the subthalamic nucleus. 

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