Other Nitrogen-Platinum Products

Reaction with hydrazines gives products of structure 

The reaction appears to be second order during the initial growth state with specific rate constants similar to those found for reaction with simple monoamines. After the initial relatively rapid growth period, product formation slows, but proceeds through several days reaction time. Reaction yields after 24 h varied from about 14% for phenylhydrazine to 70% for 4-nitrophenylhydrazine. Two tumor lines were studied. Both the L929 and HeLa were inhibited at a concentration of 12 p,g/mL. 

A number of urea, thiourea, amide, and thioamide products were synthesized. The structure for die products derived from thiourea is given in 18, and the structure for products from oxamide is given in 19. 

While the products could take on an octahedral structure, infrared evidence was consistent with a square-planar arrangement about the platinum atom. 

The chain lengths ranged from about 40 to 750. Interestingly, the chain length increased as the electron density on the amine increased. Thus, the urea product had a degree of polymerization of 37 while the corresponding thiourea product had a degree of polymerization of 750. 

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The best method for the preparation of CF3SF is the reaction of CFgSCl with HgFg in a nickel or platinum apparatus at 130°C, followed by removal of the reaction products by condensation in liquid nitrogen 144). Analogous reactions with metal fluorides lead to other sulfenyl fluorides 102,189) ... 

Like many of the nitrogen heterocycles possessing tetrahydroxybutyl side-chains (which tend to form anhydrides), the unsubstituted imidazoline-2-thione 92 readily loses water on heating its aqueous solution under pressufe,97 to give 93, and as with other 1-substituted 2-thiones, it is converted into the 1-aryl-4-(D-arabino-tetrahydroxyl-butyl)imidazole (94) by desulfurization followed by oxidation of the product with oxygen in the presence of a platinum catalyst.98... 

From the thermodynamic data of Appendix C, show that the product of the reaction of ammonia gas with oxygen would be nitrogen, rather than nitric oxide, under standard conditions and in the absence of kinetic control by, for example, specific catalysis of NO formation by platinum. (Assume the other product to be water vapor.)... 

Owing to the influence of hydrazine, at room temperature and in the presence of palladium or platinum as a catalyst, hexyl nitrate is transformed into the corresponding alcohol. Amongst other products nitrous oxide and nitrogen are formed during the same process (L. P. Kuhn [45]) ... 

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