Osteogenic bone grafts

There are two t5 es of bone tissue in the human oiganism. Cortical bone thanks to the presence of Haversian channels shows good osteoconductive properties. Thanks to its mechanical properties it can be used in cases when recreation of tridimensional cavities within the facial part of the skeleton is required. As opposed to cortical bone, cancellous bone is extremely rich in osteogenic cells. Living osteoblasts of cancellous bone may survive even for a few hours from the time of harvesting of the tissue early revascularization in closed cavities takes place after 48 hr. The disadvantage of the cancellous bone grafts is their small mechanical endurance. It is also connected with the lack of possibility to use them in case of tridimensional reconstructions [3]. 

Terheyden, H Knak, C., Jepsen, S., Palmie, S., and Rueger, D.R. Mandibular reconstruction with a prefabricated vascularized bone graft using recombinant human osteogenic protein-1 an experimental study in miniature pigs. Part I prefabrication. Int. J. Oral Maxillofac. Surg. 30 373-379, 2001. 

Cook, S.D. et al.. In vivo evaluation of recombinant human osteogenic protein (rhOP-1) implants as a bone graft substitute for spinal fusions. Spine, 19,1655,1994. 

Osteogenic graft Bone grafts that convert the AutoB, BMA [45,46]... 

---