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Organophosphorus nerve agents protection

Gill, I., Ballesteros, A. (2000). Degradation of organophosphorus nerve agents by enzyme-polymer nanocomposite efficient biocatalytic materials for personal protection and large-scale detoxification. Biotechnol. Bioeng. 70 400-10. [Pg.1062]

Pyridostigmine bromide competitively binds to nerve tissue AchE. The binding is reversible and has been shown to protect AchE against irreversible inhibition by organophosphorus nerve agents. Pyridostigmine is a quarternary compound and does not readily cross the blood-brain barrier. Thus, it is not expected to affect or protect brain AchE. Cholinesterase inhibition, which is a mechanism of action, is also responsible for toxicity. [Pg.2165]

Important measures in prevention of military casualties include adequate detection measures, physical protection, chemical prophylaxis and proper treatment. In the terrorist context, proper emergency planning is key. Treatment of poisoning by organophosphorus nerve agents is dealt with in other chapters in this volume. [Pg.212]

Willems JL, Palate BM, Vranken MA, DeBisschop HC. Delayed neuropathy by organophosphorus nerve agents. In Proceedings of the International Symposium on Protection Against Chemical Warfare Agents. Umea, Sweden National Defence Research Institute 1983. [Pg.242]

Q Nerve Agent Bioscavengers Progress in Development of a New Mode of Protection against Organophosphorus Exposure... [Pg.175]

Organophosphorus compounds (OPs) are used in agriculture as pesticides to protect crops and indoors to keep a pest-free environment. OP insecticide poisoning is a worldwide health problem, with around 3 million poisonings and 200,000 deaths annually, most of them in the developing countries [1], OPs were developed also as warfare nerve agents, and are much more toxic for mammals... [Pg.227]


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ORGANOPHOSPHORUS

Organophosphorus nerve agents

Protecting agent

Protective agent

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