Organo synthesis

Synthesis and Properties. The synthesis of (21) follows a very straightforward route based on readily accessible starting materials and on some novel reactions ia organo—inorganic sulfur chemistry (83—85), as well as on polycondensation chemistry analogous to that utilized ia the preparation of poly(alkyl/arylphosphazenes). One preparation of (21) is as follows ... 

Synthesis of aryl ketones or aldehydes from aryl tnllates or iodides and organo stannanes in ihe presence of CO and a palladum catalyst... 

Nickel compounds Hydrogenations (e.g. Raney nickel) Conversion of synthesis gas to methane Reduction of organo nitro compounds to amines Carcinogenic (nickel subsulphide). Skin sensitization... 

All that has been said in this section applies with equal force to the use of organo-lithium reagents in the synthesis of alcohols. Grignard reagents are one source of nucleophilic carbon organolithium reagents are another. Both have substantial carbanionic char acter in their- car bon-metal bonds and undergo the same kind of reaction with aldehydes and ketones. 

First synthesis of aji organo-P comp iund by J. L. Lassaigne who made alkyl phosphites from H P04 + ROH. T. Graham (who later became the Hrst President of the Chemical Society) classiHed phosphates as ortho, pyro or meta, following J. J. Berzelius s preparation of pyrophosphoric acid by heat. 

Synthesis of heterocycles with C—C bond formation, involving organo-chromium(in) reagents 99CRV991. 

C. Eabom and R. W. Bott, Synthesis and reactions of the silicon-carbon bond, Organo-metallic Compounds of the Croup IV Elements, ed. A. G. MacDiarmid, Vol. 1, Part 1. Marcel Dekker, New York (1968). 

Synthesis of hydrolytically stable siloxane-urethanes by the melt reaction of organo-hydroxy terminated siloxane oligomers with various diisocyanates have been reported i97,i98) -yhg polymers obtained by this route are reported to be soluble in cresol and displayed rubber-like properties. However the molecular weights obtained were not very high. A later report56) described the use of hydroxybutyl terminated disiloxanes in the synthesis of poly(urethane-siloxanes). No data on the characterization of the copolymers have been given. However, from our independent kinetic and synthetic studies on the same system 199), unfortunately, it is clear that these types of materials do not result in well defined multiphase copolymers. The use of low molecular weight hydroxypropyl-terminated siloxanes in the synthesis of siloxane-urethane type structures has also been reported 198). 

Allcock HR, Nelson JM, Reeves SD, Honeyman CH, and Manners I. Ambient-temperature direct synthesis of poly(organophosphazenes) via the living cationic polymerization of organo-suhstituted phosphoranimines. Macromolecules, 1997, 30, 50-53. 

The connection between hydrophobicity and tissue compatibility has been noted for classical organic polymers (19). A key feature of the polyphosphazene substitutive synthesis method is the ease with which the surface hydrophobicity or hydrophilicity can be fine-tuned by variations in the ratios of two or more different side groups. It can also be varied by chemical reactions carried out on the organo-phosphazene polymer molecules themselves or on the surfaces of the solid materials. 

The synthesis has been achieved by this last method, using an organo-cadmium reagent. 

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