Organic synthesis Drugs

A. Ganesan, Recent developments in combinatorial organic synthesis. Drug Discovery Today 7 47-55 2002. 

Use Organic synthesis, drugs, perfumes, dyes, rocket propellant. 

NFPA Health 1, Flammability 2, Reactivity 0 Uses Fragrance in cosmetics, perfumes, detergents, tech, prods. solvent for cellulose ethers and esters intennediatefor pharmaceuticals, resins, paints, etc. synthetic flavoring agent in foods and pharmaceuticals polymerization catalyst organic synthesis drug (to induce sleep) Features Sweet flavor... 

Uses Solubilizer solvent for many org. and inorg. compds., plastic films dye solvent, dye assistant for textiles mfg. of methylamine denaturing alcohol In organic synthesis drug intermediate in mfg. of ampicillin, cephaclor, etc. solder flux ingred. plasticizer in leather, cloth films, coatings stabilizer humectant in paper accelerator buffer in lacquers, explosives, cosmetics prep, of hypnotics photochemicals biocides cryoscopy vehicle in pharmaceuticals antidote... 

Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology... 

IL-based microemulsion as a green solvent has been extensively investigated in the fields of material synthesis, polymerization, biocatalysis, organic synthesis, drug release, protein extraction, and capillary electrophoresis. 

Cake Filters - These are filters that are used to remove large amounts of solids from a slurry solution. They would normally be seen in biotechnology in the primary clarification of fermentation batches and in a variety of solids removal steps seen in the production of drugs via organic synthesis. 

Chemistry, Pharmaceutical. 2. Drugs. 3. Chemistry, Organic—Synthesis. I. Mitscher, Lester A., joint author. II. Title. [DNLM 1. Chemistry, Organic. 

Combinatorial chemistry, a new chapter of organic synthesis, is now developing rapidly. This new approach to synthesizing large designed or random chemical libraries through application of solid phase synthetic methods, promises to revolutionize the process of drug discovery in the pharmaceutical industry.24... 

Schreiber, S.L. (2000) Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery. Science, 287, 1964-1969. 

The next milestone in the development of organic synthesis was the preparation of the first synthetic dye, mauveine (aniline purple) by Perkin in 1856 Perkin, 1856, 1862). This is generally regarded as the first industrial organic synthesis. It is also a remarkable example of serendipity. Perkin s goal was the synthesis of the antimalarial drug quinine by oxidation of N-allyl toluidine (Fig. 2.4). 

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