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Organic anion transport substrate requirements

Many studies have been performed to characterize the requirements for a substrate to be transported by the "organic cation transport mechanism" [97-100]. As for organic anions, the molecular structure of substrates is rather unspecific. Hydrophobicity and basicity are the general characteristics of substrates, but their ionization is not a prerequisite for interacting with the basolateral carrier [65]. Similar properties were found in brush border membrane [97-100]. Although the ratio of basolateral to apical membrane affinities may vary with substrates and animal species [97]. [Pg.57]

See other pages where Organic anion transport substrate requirements is mentioned: [Pg.506]    [Pg.322]    [Pg.423]    [Pg.367]    [Pg.52]    [Pg.642]    [Pg.80]    [Pg.29]    [Pg.38]    [Pg.117]    [Pg.275]    [Pg.62]    [Pg.47]    [Pg.219]    [Pg.238]    [Pg.210]    [Pg.4]    [Pg.4]   
See also in sourсe #XX -- [ Pg.52 ]

See also in sourсe #XX -- [ Pg.29 ]



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